therapeutic endpoint

therapeutic endpoint,

n the defining factors that denote the end of a therapeutic process, such as the return to gingival health, reduction of pocket depth, and a stable clinical attachment level.
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They are attractive targets for drugs because they provide many opportunities for multiple modes of interaction that can in principal generate a common pharmacological and therapeutic endpoint.
The primary therapeutic endpoint of the study is the subsequent reduction in luminal diameter (late loss) from the time of intervention to follow-up at six months, as measured by quantitative angiography and intravascular ultrasound.
The primary therapeutic endpoint of the APPRAISAL study is the subsequent reduction in luminal diameter (late loss) from the time ofintervention to follow-up at six months, as measured by quantitative angiography and intravascular ultrasound.
All therapeutic measurements in these seven (7) other studies were determined by exercise treadmill testing (or extent of walking), similar or identical to the therapeutic endpoint used in the CFS study.
It allows for the administration of lower levels of drugs to achieve the same therapeutic endpoints.
While these companion animal studies represent research intended for ultimate licensure of veterinary therapeutics, ACT anticipates that the trial results may be relevant to its path to clinical trials in human patients and may provide a more robust assessment of safety and therapeutic endpoints than what can be obtained from inbred rodent models.
In this example the company may impose a particular study design or use of therapeutic endpoints in a clinical study involving a healthy population to explore the possibility of obtaining data for a health claim petition (disease risk reduction) or marketing the product as a medical food with no intentions of marketing the product as a drug.
This study provides a means to do just that and should facilitate the therapeutic endpoints we seek.
He further reported that in time, therapeutic endpoints could be reset in ocular hypertension or POAG based on a patient's genetic makeup.

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