In cases when various options are possible, median therapeutic dose
seems to be a reasonable reference point, some kind of "beacon" in the ocean of generics.
The mean symptomatic improvement reported after a single injection of a therapeutic dose
of NX-1207 is in the order of that reported for much more invasive therapies such as transurethral microwave and laser ablation of the prostate and is significantly more than the improvement reported for existing approved BPH drugs.
35% of patients on the therapeutic dose
cohort remain alive at 39 to 46 months.
The company stated that the VIIBRYD 20mg therapeutic dose
is now available in pharmacies.
Pharmaceutical company Actavis (NYSE:ACT) revealed on Monday that it has received approval from the US Food and Drug Administration (FDA) for a lower therapeutic dose
of VIIBRYD (vilazodone HCl) (20mg) to accompany the 40 mg daily therapeutic dose
used to treat adult patients with Major Depressive Disorder (MDD).
Still, with the average snakebite victim requiring 500 to 1,000 milligrams, that means the researchers need u2 to 25 dozen eggs to produce one therapeutic dose
The excellent tolerability and pharmacokinetics observed so far enable us to advance to the therapeutic dose
cohorts, where we hope to demonstrate safe, sustained telomerase inhibition in the targeted tumor cells.
However, Digoxin has a narrow therapeutic window and patients can easily switch to a toxic dose from a therapeutic dose
through overdosing, slow elimination and metabolism or through interactions with other medicines.
Fuller at the Cleveland Veterans Affairs Medical Center showed no significant differences in abstinence among alcoholics on three different regimens: a therapeutic dose
of disulfiram; a dose too small to be effective; or a placebo.
The researchers hope to fine-tune their liposomes to maintain a therapeutic dose
of the drug over long periods.
In an effort to pinpoint the optimum therapeutic dose
of the drug, as well as to cure the cancer, a team of physician-researchers at the hospital gave each child infusions of 1,000 milligrams of methotrexate per square meter of body surface, in a complex treatment regimen.
It allows blood centers to efficiently conduct a single culture-based bacterial contamination test for a bacteria-free, transfusion-ready therapeutic dose