thebaine


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Related to thebaine: Buprenorphine

thebaine

 [the-ba´in]
a crystalline, poisonous, and anodyne alkaloid from opium, having properties similar to those of strychnine.

the·ba·ine

(thē-bā'ēn, -in), Avoid the mispronunciation thē'bān.
An alkaloid obtained from opium (0.3-1.5%); it resembles strychnine in its action, causing tetanic convulsions.
Synonym(s): paramorphine

thebaine

/the·baine/ (the-ba´in) a crystalline, poisonous, and anodyne alkaloid from opium, having properties similar to those of strychnine.

thebaine

(thē′bə-ēn′, thĭ-bā′ĭn)
n.
An alkaloid, C19H21NO3, obtained from the opium poppy and used in the manufacture of oxycodone and other opioids. Also called paramorphine.
References in periodicals archive ?
Alkaloids make up about 10% of the dried poppy latex of which morphine, codeine, thebaine and papaverine are the most important with morphine as the principal alkaloid (Van Wyk et al.
The researchers began with three high-morphine varieties of opium poppy and a mutant plant that makes the morphine precursors thebaine and oripavine but can't make morphine itself.
that will yield economically attractive levels of morphinane alkaloids, particularly thebaine.
We confirmed that plants of this species are good sources of thebaine but, unlike the opium poppy, do not contain morphine or codeine.
somniferum does not possess the biosynthetic capacity to demethylate thebaine to allow the accumulation of morphine.
has acquired an exclusive license for a novel and highly efficient technology for isolating thebaine from raw poppy.
2 Hydrocodone 34 102 6-Monoacetylmorphine 42 28 Dihydromorphine 18 Thebaine 5 Meperidine 1 Hydromorphone 16 19 Methamphetamine D-Methamphetamine 100 100 L-Methamphetamine 8 271 Methylenedioxymethamphetamine 135 1513 D-Amphetamine 2 1.
Bhutani says the unit will convert morphine, codeine and thebaine alkaloids into superior bulk alkaloids and dosage forms that are currently unavailable in India and most other developing nations.
Whether grown or purchased, fresh or dried, these seedpods contain significant quantities of morphine, codeine, and thebaine, the principal alkaloids found in opium.
OTCBB-HDGC) today announced that it has acquired an exclusive license for a novel and highly efficient technology for isolating thebaine from raw poppy.
5 Buprenorphine, a semisynthetic thebaine derivative is more potent than morphine, pethidine, pentozocine and the duration of analgesia is longer than all.
Like apomorphine, also buprenorphine (a semisynthetic opioid derived from thebaine, naturally occurring alkaloid of Papaver somniferum, and used as substitution therapy in the treatment of opioid dependence), undergoes extensive first-pass metabolism and therefore has very low oral bioavailability (Elkader and Sproule 2005).