thalidomide neuropathy

A severe polyneuropathy seen in up 25% of those treated with thalidomide, which induces a dose-dependent sensorimotor length-dependent axonal neuropathy; it should be judiciously used with close neurologic monitoring

thalidomide neuropathy

Neurology A severe polyneuropathy seen in up 25% of those treated with thalidomide as a sedative, or higher in GVHD; in half, sensory loss is permanent.
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72) Reduction of sensory nerve action potential amplitude and relative conservation of nerve conduction velocities were the electrophysiological features of thalidomide neuropathy in 13 individuals without leprosy who were taking thalidomide for severe dermatological conditions.