thalassemia intermedia


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Related to thalassemia intermedia: Thalassemia minor

thal·as·se·mi·a in·ter·me·di·a

a clinical variant of thalassemia characterized by an intermediate degree of severity. These patients have severe anemia but usually do not require regular blood transfusions. Intermedia disorders represent a heterogeneous group of genetic disorders and may include cases with homozygous or heterozygous abnormalities in the β-globin chain gene.
Farlex Partner Medical Dictionary © Farlex 2012

thalassemia intermedia

A chronic hemolytic anemia caused by deficient alpha chain synthesis.
Synonym: hemoglobin H disease
See also: thalassemia
Medical Dictionary, © 2009 Farlex and Partners
References in periodicals archive ?
In general, pregnancy in thalassemia intermedia patients can be complicated with automatic miscarriages, fetal loss, preterm delivery, IUGR, and thrombosis [11].
Genetic interactions in thalassemia intermedia: analysis of beta-mutations, alpha-genotype, gamma-promoters, and beta-LCR hypersensitive sites 2 and 4 in Italian patients.
Values for IRM, PLT-I, PLT-O, and PLT-F were not significantly different among thalassemia minor, thalassemia intermedia, and thalassemia major.
Giant myelolipoma in a patient with thalassemia intermedia. Am J Hematol 2000; 65: 265-266.
Molecular characterization of thalassemia intermedia, due to coinheritance of homozygous alpha triplication and IVSI-5 beta-thalassemia.
We classified the patients as thalassemia major if they required transfusion more than eight times till the age of 8 years, while thalassemia intermedia patients are those with no or occasional transfusion before the age of 4 years.
Other hemoglobin disorders like Beta thalassemia intermedia, sickle cell trait, sickle cell/beta thalassemia, HbE disorder were collectively detected in 25 (11.0%) cases.
Hematologic and clinical responses of thalassemia intermedia patients to hydroxyurea during 6 years of therapy in Iran.
Piga et al., "Butyrate + EPO in beta thalassemia intermedia: interim findings ofa phase II trial," Blood, vol.
Papassotiriou et al., "Unstable and thalassemic a chain hemoglobin variants: a cause of Hb H disease and thalassemia intermedia," Hemoglobin, vol.