thalassemia intermedia


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Related to thalassemia intermedia: Thalassemia minor

thal·as·se·mi·a in·ter·me·di·a

a clinical variant of thalassemia characterized by an intermediate degree of severity. These patients have severe anemia but usually do not require regular blood transfusions. Intermedia disorders represent a heterogeneous group of genetic disorders and may include cases with homozygous or heterozygous abnormalities in the β-globin chain gene.

thalassemia intermedia

A chronic hemolytic anemia caused by deficient alpha chain synthesis.
Synonym: hemoglobin H disease
See also: thalassemia
References in periodicals archive ?
Molecular characterization of thalassemia intermedia, due to co-inheritance of homozygous alpha triplication and IVSI-5 beta-thalassemia.
b) Thalassemia intermedia includes Hb H disease, Hb H disease with CS, AE Bart disease, and EF Bart disease.
Independent sample T test was used to compare between patients and control and between patients of thalassemia major and thalassemia intermedia with respect to father's age, mother's age, and state of consanguinity.
Hematologic and clinical responses of thalassemia intermedia patients to hydroxyurea during 6 years of therapy in Iran.
Compound heterozygotes involving HbE/[beta]-thalassemia have become a diagnostic concern among Southeast Asian populations where HbE is prevalent because the co-inheritance of [beta]-thalassemia with HbE manifests as thalassemia intermedia.
The effect of dietary magnesium supplementation on the cellular abnormalities of erythrocytes in patients with beta thalassemia intermedia.
An interesting presentation of intrathoracic extramedullary hematopoiesis In a patient with thalassemia intermedia.
The condition ranges from thalassemia minor, the trait that causes a mild microcytic anemia, which does not need treatment, to thalassemia intermedia, a complicated condition needing physician attention in which blood transfusions improve the patient's quality of life, to thalassemia major, a complex illness needing extensive and ongoing medical treatment.