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having a valence of four.
Miller-Keane Encyclopedia and Dictionary of Medicine, Nursing, and Allied Health, Seventh Edition. © 2003 by Saunders, an imprint of Elsevier, Inc. All rights reserved.


Having the combining power (valency) of four.
Synonym(s): tetravalent
Farlex Partner Medical Dictionary © Farlex 2012


1. Chemistry Having valence 4.
2. Immunology
a. Having four sites of attachment. Used of an antibody or antigen.
b. Containing antigens from four strains of a microorganism or virus. Used of a vaccine or serum.
The American Heritage® Medical Dictionary Copyright © 2007, 2004 by Houghton Mifflin Company. Published by Houghton Mifflin Company. All rights reserved.


Having the combining power (valency) of four.
Synonym(s): tetravalent.
Medical Dictionary for the Health Professions and Nursing © Farlex 2012
References in periodicals archive ?
Previous efforts for developing recombinant tetravalent EDIII vaccines used different approaches.
HPV9 is similar in composition to the tetravalent vaccine, using virus-like particles to elicit immune responses [8].
Evaluation of genotoxicity of oral exposure to tetravalent vanadium in vivo.
Menomune (Meningococcal Polysaccharide Vaccine, Groups A, C, Y, and W-135 Combined) is the brand name for Sanofi's tetravalent polysaccharide vaccine sold in the US and Australia to protect against four N.
Currently, tetravalent conjugate vaccines, such as Sanofi's Menactra and Novartis' Menveo, account for the vast majority of global sales, with the US adolescent market being the key target segment.
We are cautiously optimistic about these recent clinical trial results with this candidate tetravalent vaccine developed at NIAID; however, much more work still needs to be done," said NIAID director Anthony S.
Le Maroc dispose du vaccin tetravalent contre les meningocoques, des serogroupes A, C, Y, W135.
(http://dx.doi.org/10.1016/S0140-6736%2812%2961428-7) "Protective efficacy of therecombinant, live-attenuated, CYD tetravalent dengue vaccine in Thai schoolchildren: a randomized, controlled phase 2b trial" ; Halstead, Scott.
In a study published last year, more than 20,000 parents were surveyed in 2009 on their adolescent's immunization status for three vaccines: tetanus/diphtheria or tetatnus/diphtheria/pertussis (Td/Tdap), tetravalent meningitis (MenACWY) and human papillomavirus (HPV).
Meningococcal polysaccharide vaccines are available in either bivalent (groups A and C), trivalent (groups A, C and W), or tetravalent (groups A, C, Y and W135) forms to control the disease.
Later in 2006 GAVI introduced tetravalent vaccine (DPT with Hepatitis B) and thus the vaccination schedule moved to 6, 10 and 14 weeks.
Dr Fikri also said that based on World Health Organisation recommendations, the ministry is also considering new vaccines such as for Rotavirus (severe diarrhea), Cervical Cancer, Acellular Tetravalent (Diptheria-Tetaus) and Varicella (Chickenpox).