methionine synthase(redirected from tetrahydrofolate methyltransferase)
tetrahydropteroylglutamate methyltransferase; methionine-homocysteine methyltransferase; an enzyme that catalyzes the reaction of N5-methyltetrahydrofolate with l-homocysteine to form tetrahydrofolate and l-methionine; a cobalamin-requiring enzyme; a deficiency of this enzyme results in an accumulation of l-homocysteine and neurological abnormalities.
Synonym(s): tetrahydrofolate methyltransferase
methionine synthase(1) 5-Methyltetrahydrofolate-homocysteine S-methyltransferase, EC 188.8.131.52.
(2) O-Acetylhomoserine (thiol)-lyase, EC 184.108.40.206.