methionine synthase(redirected from tetrahydrofolate methyltransferase)
tetrahydropteroylglutamate methyltransferase; methionine-homocysteine methyltransferase; an enzyme that catalyzes the reaction of N5-methyltetrahydrofolate with l-homocysteine to form tetrahydrofolate and l-methionine; a cobalamin-requiring enzyme; a deficiency of this enzyme results in an accumulation of l-homocysteine and neurological abnormalities.
Synonym(s): tetrahydrofolate methyltransferase
methionine synthase(1) 5-Methyltetrahydrofolate-homocysteine S-methyltransferase, EC 220.127.116.11.
(2) O-Acetylhomoserine (thiol)-lyase, EC 18.104.22.168.