The activity of the quaternary protoberberinium salts with an aromatic ring C such as berberine was higher than that of the quaternary salts such as the N-metho- salts or the N-oxides of tetrahydro-
and dihydroderivatives as well as tertiary tetrahydroproto-berberines.
Wt.: 332.43; C, 72.26; H, 8.49; 496.59; C, 62.88; H, 8.12; 0,19.25 IUPAC: 3-(2-((lR,4aS, O, 29.00 5R,8aS)-decahydro-l- (hydroxymethyl)-l,4a-dimethyl- IUPAC: 3-(2-((lR,2R,4aS,5R, 6-methylene-2-oxonaphthalen- 8aS)-decahydro-l- 5-yl)ethyl)furan-2(5H)-one (hydroxymethyl)-l,4a-dimethyl- 6-methylene-2-(tetrahydro-
Part used: AeP 3,4,5-trihydroxy-6- (hydroxymethyl)-2H-pyran-2- Extracts: E (#) yloxy)naphthalen-5-yl)ethyl) furan-2(5H)-one Pharmacology: antiproliferative  Part used: AeP Extracts: AW ([dagger]) Pharmacology: antimicrobial  3-O-beta-D-glucopyranosyl- 8,17-Epoxy-14- andrographolide deoxyandrographolide Chemical properties: Chemical properties: [C.sub.26][H.sub.40][O.sub.10] [C.sub.20][H.sub.32][O.sub.5] Exact mass: 512.26; Mol.
etiocholanolone Aldosterone Allo-tetrahydro- corticosterone Tetra hydrocorticosterone 11-dehydro tetrahydro-
corticosterone TSH Not available Free T3 T4 (Total Free T4 and/or free) T3 (Total THE/THF ratio and/or free) rT3 Thyroid antibodies Commentary: Serum panels are standard for thyroid evaluation and have the most comprehensive panels.
Other derivatives, including the dihydro- and tetrahydro-
compounds have also been prepared and characterized, and are being used in a structure-function study.
Similarly obtained were tetrahydro-
and hexahydroiso-humulones 4 (calcd for [C.sub.21][H.sub.34][O.sub.5]) and -6 (calcd for [C.sub.21][H.sub.36][0.sub.5]), prepared by hydrogenation of isohumulones 3, and reduced isohumulones 5, respectively, in the presence of 5% palladium on charcoal (Pd/C) in water at [p.sub.H] 10.
ReagentsAnalaR grade chemicals: 4- Florobenzaldehyde, 1,4-naphthquinone, ethylenediamine, m-creosol, n-hexane, tetrahydro-
furan (THF), dimethylformamide (DMF), dimethylacetamide (DMAc), dimethylsulphoxide (DMSO), NiCl2 and CuCl2 were obtained from Fluka, Switerzerland).