tetanus toxoid

Also found in: Dictionary, Thesaurus, Acronyms, Encyclopedia.


a toxin treated by heat or chemical agent to destroy its deleterious properties without destroying its ability to combine with or stimulate the formation of antitoxin.
diphtheria toxoid a sterile preparation of formaldehyde-treated products of the growth of Corynebacterium diphtheriae, used as an active immunizing agent, generally in mixtures with tetanus toxoid and pertussis vaccine (DTP) or with tetanus toxoid alone (DT for pediatric use and Td, which contains less diphtheria toxoid, for adult use).
tetanus toxoid a sterile preparation of formaldehyde-treated products of the growth of Clostridium tetani, used as an active immunizing agent, either in mixtures with diphtheria toxoid and pertussis vaccine (DTP, DT, Td) or by itself (T).
Miller-Keane Encyclopedia and Dictionary of Medicine, Nursing, and Allied Health, Seventh Edition. © 2003 by Saunders, an imprint of Elsevier, Inc. All rights reserved.

tetanus toxoid

 A small peptide fragment that selectively elicits helper immune response but not immune suppression
McGraw-Hill Concise Dictionary of Modern Medicine. © 2002 by The McGraw-Hill Companies, Inc.

Tetanus toxoid

Tetanus toxoid is a vaccine used to prevent tetanus (also known as lockjaw).
Mentioned in: Clenched Fist Injury
Gale Encyclopedia of Medicine. Copyright 2008 The Gale Group, Inc. All rights reserved.
References in periodicals archive ?
Overall, the tetanus toxoid coverage among pregnant respondents of present study was satisfactory as 85% of pregnant women were vaccinated with atleast two doses of TT during their current pregnancy at health care facility which is higher than another local study which showed that tetanus toxoid coverage was only 43% and such percentage is much lower than recommended by World Health Organization (WHO) i.e.
In this regard, other studies should be conducted aiming at determining the proportion of tetanus toxoid immunization status of mothers by antibody testing to know the absolute proportion of mothers protected tetanus at birth.
In a November 2014 statement, the CDC said, "There is not, and never was, human chorionic gonadotropin (HCG) in any Tetanus Toxoid (TT) vaccine used for tetanus prevention" by UNICEF or WHO.
Updated recommendations for use of tetanus toxoid, reduced diphtheria toxoid, and acellular pertussis vaccine (Tdap) in pregnant women--Advisory Committee on Immunization Practices (ACIP), 2012.
INTRODUCTION: A 48 years old male married Hindu; assistant agriculture officer from Imphal attended Psychiatric OPD with the chief complaints of repeated checking of his house and its premise, repeated washing of hands, feet and clothes and injecting tetanus toxoid almost every day for duration of five years.
Tetanus was well known to the ancients; Greek physician Aretaeus wrote in the first century ce, "Tetanus in all its varieties, is a spasm of an exceedingly painful nature, very swift to prove fatal, but neither easy to be removed." Active immunization with tetanus toxoid was described in 1890, but cases continue to be reported (275 in the United States from 2001 through 2010), almost exclusively in persons who were never vaccinated or had not received a booster immunization in the previous 10 years.
Bingham, director of the rheumatology clinics at John Hopkins University in Baltimore, reported that relative to patients treated with methotrexate only, patients who were given rituximab plus methotrexate mount a comparable recall response to tetanus toxoid, a measure of retained immunity.
A new tool is now available to assist in controlling pertussis: the tetanus toxoid, reduced diphtheria toxoid, and acellular pertussis vaccine (Tdap).
The tetanus toxoid, reduced diphtheria toxoid, and acellular pertussis vaccine, adsorbed (Tdap) was licensed in June for use as a single-dose booster immunization in persons aged 11-64 and was previously recommended by ACIP for use in adolescents.
Those of us who were immunized in infancy received a triple vaccine, DPT, containing diphtheria, pertussis (whooping cough), and tetanus toxoid. If first immunized in military service, we were given Td, a dual vaccine that omits the pertussis toxoid and contains a smaller amount of diphtheria toxoid, which can cause adverse reactions in adults.
They identified the compound in each step by measuring the ability of various fractions to inhibit the proliferation of immune cells stimulated with tetanus toxoid.