testotoxicosis

tes·to·tox·i·co·sis

(tes'tō-toks'i-kō'sis),
A G protein mutation disease resulting in autonomous testosterone overproduction, with precocious puberty.
Farlex Partner Medical Dictionary © Farlex 2012

testotoxicosis

A state of ♂ precocious puberty characterized by autonomous testicular production of androgen, requiring antiandrogens and aromatase inhibitors to slow skeletal growth to a prepubertal rate
McGraw-Hill Concise Dictionary of Modern Medicine. © 2002 by The McGraw-Hill Companies, Inc.

tes·to·tox·i·co·sis

(tes'tō-tok-si-kō'sis)
A G-protein mutation disease resulting in autonomous testosterone overproduction, with precocious puberty.
Medical Dictionary for the Health Professions and Nursing © Farlex 2012

testotoxicosis

(tĕs″tō-tŏk″sĭ-kō′sĭs) [″ + ″]
Precocious puberty occurring in boys due to increased secretion of the male hormone, testosterone. Affected boys prematurely develop adult secondary sexual characteristics, increased height and muscle mass, and, in some instances, aggressive behavior.
Medical Dictionary, © 2009 Farlex and Partners
References in periodicals archive ?
I have reviewed the letter to the editor regarding "Testotoxicosis: Report of Two Cases, One with a Novel Mutation in LHCGR Gene".
Defects in receptors or signaling typically lead to loss-of-function conditions (e.g., glucocorticoid, mineralocorticoid, or androgen resistance) although gain-of-function mutations do occur (e.g., testotoxicosis or the McCune-Albright syndrome).
Defects in receptors or signaling typically lead to loss-of-function conditions (e.g., glucocorticoid, mineral-ocorticoid, or androgen resistance) although gainof-function mutations do occur (e.g., testotoxicosis or the McCune-Albright syndrome).