A G protein mutation disease resulting in autonomous testosterone overproduction, with precocious puberty.
testotoxicosisA state of ♂ precocious puberty characterized by autonomous testicular production of androgen, requiring antiandrogens and aromatase inhibitors to slow skeletal growth to a prepubertal rate
A G-protein mutation disease resulting in autonomous testosterone overproduction, with precocious puberty.
testotoxicosis(tĕs″tō-tŏk″sĭ-kō′sĭs) [″ + ″]
Precocious puberty occurring in boys due to increased secretion of the male hormone, testosterone. Affected boys prematurely develop adult secondary sexual characteristics, increased height and muscle mass, and, in some instances, aggressive behavior.