testolactone

testolactone

[tes′təlak′tōn]
an antineoplastic androgen analog.
indications It is prescribed as palliative treatment of advanced postmenopausal breast cancer and in premenopausal women whose ovarian function has been terminated.
contraindications Pregnancy, lactation, or known hypersensitivity to this drug prohibits its use. It is not given to men.
adverse effects Among the more serious adverse effects are hypercalcemia and peripheral neuropathies with numbness or tingling.

testolactone

(tĕs-tō-lăk′tōn)
An antineoplastic agent used in treating carcinoma of the breast in postmenopausal women.
References in periodicals archive ?
Aromatase inhibitors, including but not limited to: aminoglutethimide, anastrozole, exemestane, formestane, letrozole, testolactone
Waddell WR, Kirsch WM: Testolactone, sulindac, warfarin and vitamin K1 for unresectable desmoid tumors.
Aromatase inhibitors such as testolactone, anastrozole, and letrozole can decrease the synthesis of estrogen by inhibiting aromatization of androgens.
16) Antiestrogen drugs such as tamoxifen and testolactone have been used in selected cases with success.
A case treated effectively by testolactone with a long follow-up study.
Treatment of precocious puberty in the McCune-Albright syndrome with the aromatase inhibitor testolactone.