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tes·tis-·de·ter·min·ing fac·tor (TDF),
the product of a gene on the short arm of the Y chromosome that is responsible for production of the testes.
testis-determining factorA protein encoded by a gene in the SYR region on the short arm of the Y chromosome, which is responsible for development of 1º ♂ organs. See X-chromosome inactivation.
a single gene on the short arm of the Y chromosome.