tertiary syphilis


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late syph·i·lis

involvement of the cardiovascular or central nervous system, or the development of a gumma in any organ, due to infection with Treponema pallidum; usually occurs several years to 2-3 decades after the initial infection.
Synonym(s): tertiary syphilis

tertiary syphilis

n.
The final stage of syphilis, following a latent period that may last years, marked by spread of the disease throughout the body including the skin, bones, joints, heart, brain, and spinal cord.

tertiary syphilis

Late syphilis STD A late phase of syphilis preceded, often by many yrs, by primary and secondary syphilis, caused by the spirochetes of Treponema pallidum which continued to reproduce for up to 15 years; focal damage in the form of highly destructive gummas occurs in bone, skin, nervous tissue, heart, arteries; neurosyphilis has many clinical forms–tabes dorsalis, general paresis and optic atrophy; cardiovascular involvement leads to aortic aneurysms, valvular heart disease, aortitis. See Benign late syphilis, Congenital syphilis, Latent syphilis, Neurosyphilis, Primary syphilis, Secondary syphilis, Syphilis.
References in periodicals archive ?
The duration of treatment ranged from 2 to 3 weeks, although 2 patients received a total of 4 weeks of treatment (1 who was treated first with doxycycline and 1 who was diagnosed with tertiary syphilis).
In tertiary syphilis with bone involvement, PET showed increased uptake of FDG at the bone.[sup][37]
Tertiary syphilis in the antibiotic era is rare and tertiary syphilis in HIV-uninfected and HIV-infected patients is vanishingly rare.
(3,4) Approximately half of patients with tertiary syphilis presents "benign" late syphilis with gums emergence.
Tertiary syphilis (late syphilis) is not mandatory.
"The symptoms of tertiary syphilis, which will occur many years after acquiring infection, can be dangerous enough to cause death."
Neurosyphilis is regarded as a manifestation of tertiary syphilis, but the spirochete may invade the central nervous system early in the course of infection.
Because primary and secondary syphilis can run their course unnoticed, the risk of latent and deadly tertiary syphilis cannot he ignored.
The account concludes, movingly, with Theo's terrible end, paralytic and insane due to tertiary syphilis, just six months after his brother's.
Late complications of syphilis, known as tertiary syphilis, can manifest as three general categories of symptoms.
The histopathological differential diagnosis includes other orofacial granulomatous conditions such as sarcoid, Crohn's disease, deep mycoses, cat-scratch disease, foreign-body reactions, tertiary syphilis and Melkersson-Rosenthal syndrome.
Syphiloma (gumma syphilitica)--deep syphilides that develops in the subcutaneous tissue in patients with tertiary syphilis. It characterized as follows: the rise above the skin, increasing in size, firm elastic consistency, painless, first mobility, and in the future--cohesion with the surrounding tissues, the color of pink, purple to black, clear boundaries.