termination factor

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re·leas·ing fac·tors (RF),

1. any substance, usually of hypothalamic origin, capable of accelerating the rate of secretion of a given hormone by the anterior pituitary gland;
2. factors required in the termination phase of either RNA biosynthesis or protein biosynthesis. Synonym(s): termination factor
3. colloquial shortened form for the HMG-CoA reductase inhibitors used as antihyperlipidemic agents, whose generic names end with the suffix statin. Synonym(s): statins

termination factor

one of a group of special proteins that mediates termination of protein synthesis by recognizing a TERMINATION CODON in mRNA and bringing about the release of the ribosomal subunits. Also called release factor (RF). see TRANSLATION.
References in periodicals archive ?
Cleavage of TAR by Microprocessor has major consequences 1) it provides a substrate for Rrp6, which generates a small RNA that represses HIV-1 transcription, 2) it creates an entry site for Xrn2 and termination factors that lead to premature termination of transcription.
Our research supports this conclusion and reveals further that considerable differences exist indeed among the key termination factors at each stage.
According to Smith and Alpert, police pursuit policies should include a mission statement, legal authorization for pursuits, continuation and termination factors, and detailed responsibilities for support units, supervisors, and communications personnel.

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