Termination factor | definition of termination factor by Medical dictionary
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re·leas·ing fac·tors (RF),
1. any substance, usually of hypothalamic origin, capable of accelerating the rate of secretion of a given hormone by the anterior pituitary gland;
factors required in the termination phase of either RNA biosynthesis or protein biosynthesis. Synonym(s): termination factor
colloquial shortened form for the HMG-CoA reductase inhibitors used as antihyperlipidemic agents, whose generic names end with the suffix statin. Synonym(s): statins
termination factor one of a group of special proteins that mediates termination of protein synthesis by recognizing a TERMINATION CODON in mRNA and bringing about the release of the ribosomal subunits. Also called release factor (RF). see TRANSLATION.
References in periodicals archive
Topics include reconstruction of glutamine synthetase using computer averaging, a cryo-electron microscopic study of ribosome-bound termination factor
RF2, the process of mRNA-tRNA translocation, and the structural basis for gating and activation of RyR1.
"Are R&D Project Termination Factors
Universal?" Research * Technology Management, July-Aug., 1995, pp.