terminal deoxynucleotidyl transferase


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terminal deoxynucleotidyl transferase (TdT),

a specialized DNA polymerase expressed in immature, pre-B, pre-T lymphoid cells, and acute lymphoblastic leukemia/lymphoma cells.

ter·mi·nal de·ox·y·nu·cle·o·ti·dyl trans·fer·ase

(TdT) (tĕr'mi-năl dē-oks'ē-nū-klē-ō-tī'dil trans'fĕr-ās)
A specialized DNA polymerase expressed in immature, pre-B, pre-T lymphoid cells, and acute lymphoblastic leukemia/lymphoma cells.
References in periodicals archive ?
The terminal deoxynucleotidyl transferase dUTP nick end labeling (TUNEL)-based in situ Cell Death Detection Kit, Fluorescein (Roche, Nutley, NJ, USA) was used to detect the apoptosis of the photoreceptor cells in the sections.
European Group for Immunological Characterization of Acute Leukemias (EGIL) Algorithm for Biphenotypic Blasts (a,b) Points B T Myeloid 2 cyCD79a CD3 (sm or cy) MPO cyCD22 TCR-[alpha][beta] cyIgM TCR-[gamma][delta] 1 CD19 CD2 CD117 CD20 CD5 CD13 CD10 CD8 CD33 CD10 CDw65 0.5 TdT TdT CD14 CD24 CD7 CD15 CD1a CD64 Abbreviations: cy, cytoplasmic; IgM, immunoglobulin M; MPO, myeloperoxidase; sm, surface membrane;TCR, T-cell receptor;TdT, terminal deoxynucleotidyl transferase. (a) Biphenotypic leukemia is diagnosed when scores are greater than 2 in 2 lineage columns.
Keywords: Behcet disease, neuro-Behcet disease, immunoglobulin G, terminal deoxynucleotidyl transferase dUTP nick end labeling, neurotoxicity
ATO: atorvastatin; CI-AKI: contrast-induced acute kidney injury; DAPI: 4,,6-diamino-2-phenylindole; RUS: rosuvastatin; SSTN: simvastatin; TUNEL: terminal deoxynucleotidyl transferase dUTP nick-end labeling.
Determination of cell apoptosis in xenograft of colon cancer by Terminal Deoxynucleotidyl Transferase dUTP Nick-end Labeling (TUNEL)
Cell death was detected using the Terminal deoxynucleotidyl transferase dUTP nick end labeling (TUNEL) assay at various capsaicin concentrations and exposure times.
In vitro terminal deoxynucleotidyl transferase dUTP nick-end labeling (TUNEL) assay
After removing the 70% ethanol by centrifugation, the cells were washed twice in wash buffer and then incubated at 37[degrees] C for 60 min with DNA-labeling solution containing terminal deoxynucleotidyl transferase and BrdUTP.
Apoptotic cells were detected by terminal deoxynucleotidyl transferase mediated deoxy-UTP nick end labeling (TUNEL), using an in situ detection kit (Roche Diagnostic, Manheim, Germany).
The slides were immersed in terminal deoxynucleotidyl transferase (TdT) buffer.
Apoptotic cells were detected by using terminal deoxynucleotidyl transferase (TdT)- mediated dUTP nick end labeling (TUNEL) detection kit (GenScript, USA), which is a sort of an immunohistochemical technique.
Retinal cell damage was also detected with Terminal deoxynucleotidyl transferase dUTP nick end labeling (TUNEL) staining at 48h after light exposure.

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