terbinafine


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terbinafine

 [ter´bin-ah-fēn″]
a synthetic antifungal agent used as the hydrochloride salt topically and orally in treatment of tinea and of fungal infections of the nails.

terbinafine

/ter·bin·a·fine/ (ter´bĭ-nah-fēn″) a synthetic antifungal used as the hydrochloride salt in the treatment of tinea and onychomycosis.

terbinafine

(tər-bĭn′ə-fēn′, tûr′bĭ-nə-fēn′)
n.
An antifungal drug, C21H25N5, used in the form of its hydrochloride to treat onychomycosis.

terbinafine

Lamisil® An antifungal that is better than griseofulvin for treating onychomycosis

terbinafine

An antifungal drug that acts by causing leakage of the fungal cell contents through the fungal cell wall. It is especially useful against TINEA of the skin and nails for which it is said to be more effective than clotrimazole. A brand name is Lamisil.

terbinafine

an antifungal agent used as the hydrochloride in the treatment of fungal skin infections and particularly those involving the nails.
References in periodicals archive ?
corporis were treated with oral Terbinafine 250 mg once daily for two weeks and topical cream for another 4 weeks.
Itraconazole pulse therapy vs continuous terbinafine dosing for toenail onychomycosis.
Terbinafine (Lamisil, Novartis, East Hanover, NJ, USA) was released in 1996 for treatment of human mycotic nail infections (11) but has received limited assessment and clinical use as a potential therapeutic agent in avian species.
Conclusion: Taking antifungal activity of terbinafine as 100%, it was 66% with Aloe vera and 47% with Cymbopogon citratus which are considered intermediate.
Our patient's medical history indicated an exposure to terbinafine within 1 week before her skin eruption.
All the strains were subjected to biofilm formation under the following growth conditions separately: YNB with 50 mM glucose, YNB with 50 mM Glucose supplemented with 500 [micro]M AA (Sigma Aldrich, USA), YNB with 50 mM glucose added subinhibitory concentration (1/2MIC) of fluconazole, YNB with 50 mM glucose added 1/2MIC terbinafine, YNB and 50 mM glucose supplemented with 1/2MIC fluconazole and AA and YNB supplemented with 50 mM glucose, 1/2MIC terbinafine and AA.
Pulsed-dose therapy with terbinafine is not FDA approved.
However, patients who have diabetes or are older than 65 years who take terbinafine along with antihypertensives, lipid-lowering agents, or "diabetic medications," don't manifest abnormal serum liver enzymes, creatinine, or glucose levels in the short term (SOR: C, 2 small cohort studies with disease-oriented outcomes).
Terbinafine is a widely prescribed oral antifungal agent.
The only other approved drug is terbinafine granules, and these are hard to obtain, he said, but itraconazole and fluconazole might work.
Currently, griseofulvin (Grifulvin[R]) and terbinafine (Lamasil Granules[R]) are the only two medications approved by the United States Food and Drug Administration (FDA) for the treatment of tinea capitis (FDA, 2007; Roberts & Friedlander, 2005).