terbinafine


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Related to terbinafine: itraconazole, Lamisil, Terbinafine hydrochloride

terbinafine

 [ter´bin-ah-fēn″]
a synthetic antifungal agent used as the hydrochloride salt topically and orally in treatment of tinea and of fungal infections of the nails.

terbinafine

/ter·bin·a·fine/ (ter´bĭ-nah-fēn″) a synthetic antifungal used as the hydrochloride salt in the treatment of tinea and onychomycosis.

terbinafine

(tər-bĭn′ə-fēn′, tûr′bĭ-nə-fēn′)
n.
An antifungal drug, C21H25N5, used in the form of its hydrochloride to treat onychomycosis.

terbinafine

Lamisil® An antifungal that is better than griseofulvin for treating onychomycosis

terbinafine

An antifungal drug that acts by causing leakage of the fungal cell contents through the fungal cell wall. It is especially useful against TINEA of the skin and nails for which it is said to be more effective than clotrimazole. A brand name is Lamisil.

terbinafine

; Lamisil topical/systemic fungicidal agent; prevents formation of normal fungal cell walls (has inhibitory action on cellular squalene epioxidase); oral dose = 250mg daily for 2-6 weeks for tinea pedis, or 6 to >12 weeks for onychomycosis (note: must be used with caution on patients with cardiac arrhythmia and those taking drugs that prolong cardiac QT interval); topical dose for skin infections = 1% cream for 7 days for tinea pedis, or as topical single-dose formulation (e.g. Lamisil Once)

terbinafine

an antifungal agent used as the hydrochloride in the treatment of fungal skin infections and particularly those involving the nails.
References in periodicals archive ?
Bakuchiol, the antifungal drug terbinafine and the positive control nystatin were all able to increase the uptake of SYTOX[R] Green into fungal cells significantly and dose-dependently (Fig.
After oral administration of terbinafine, the maximum concentration for the remaining 5 fed birds ranged from 109 to 671 ng/mL, half-life ranged from 6 to 13.
Robbins also tried injecting terbinafine directly into white-nose-infected little brown bats that she brought back to her lab from a cave in Virginia.
Athlete's Foot is a large and well understood market, with terbinafine the gold standard therapy.
125 ([double dagger]) Caspofungin Terbinafine Isolate MEC, mg/L MIC, mg/L Patient 1 0.
In addition to terbinafine tablets, FDA also approved an application for a generic version of over-the-counter Lamisil cream (terbinafine hydrochloride, 1 percent) to treat athlete's foot, a skin disease caused by a fungus that usually occurs between the toes.
The Medicines Control Agency has recently reviewed the safety of terbinafine and concluded that its benefits outweigh its risks.
Terbinafine, on the other hand, can be safely taken with Seldane.
A combination of amorolfine nail lacquer and oral terbinafine is the most commonly used combination therapy.
High throughput screening synergy assay Baccharis species Ent-clerodanes Flavonoids Trichophyton rubrum Terbinafine Antifungal Synergism Additivism 3D surface--response curves CombiTool software
Systemic Theropy Fingernails Fluconazole (3) * 3 to 8 mg/kg pulsed-dose weekly for 6 weeks OR 200 mg/week for 8 to 16 weeks Itraconazole (4) 400 mg/day for 1 week/month, repeated for 2 or 3 months (dagger) Terbinafine (7) 250 mg/day for 6 weeks Toenails Fluconazole (3) 200 mg/week for 12 to 24 weeks Itraconazole (5) 400 mg/day for 1 week/month, repeated for 3 or 4 months (double dagger) Terbinafine (7) 250 mg/day for 12 weeks * Although it is commonly used for onychomycosis, this is not an FDA-approved indication for fluconazole.
Terbinafine hydrochloride offers numerous potential benefits over traditionally used antifungals for treatment of this disease.