The clinical picture is highly variable, but the major characteristics include hypertelorism, primary telecanthus
, median nasal cleft with a broad nasal root, and a widow's peak hairline [4,10].
1) Previous reports demonstrated ocular manifestations of trisomy 9 patients as deeply-set eyes, small palpebral fissures, telecanthus
, keratolenticular adhesion and marked iris hypoplasia.
She had frontal bossing, telecanthus
, slightly depressed nasal bridge and prominent nasal tip.
64%) came with congenital Blepharophimosis syndrome, telecanthus
, cerebral palsy, mental retardation, dental malformations, bat ears, convergent squint with developmental delay and came to diagnosed as a syndrome of oculo-cerebro-dento-auricular malformations (CODAS) syndrome a rare autosomal recessive syndrome with <1/1000000 incidence.
Orbital hypertelorism is increased distance between medial orbital walls and telecanthus
is increased distance between medial canthi4.
Craniofacial findings includes dolichocephaly, high prominent forehead, ocular proptosis, hypertelorism, telecanthus
, downslanting palpebral fissures, maxillary hypoplasia, cleft palate with prominent palatine ridges, micrognathia, and apparently low-set and posteriorly rotated ears.
On examination there was a 4x5 cm cystic swelling associated with telecanthus
Toriello-Carey syndrome is a rare multiple congenital anomaly syndrome comprising ACC, telecanthus
, short palpebral fissures, abnormal ears, Pierre Robin sequence, and cardiac anomaly .
Blepharoptosis, blepharophimosis, epicanthus inversus, and telecanthus
a syndrome with no name.
Another reported feature of this syndrome is congenital ptosis that in some cases may be associated with hypertelorism and telecanthus
[Bamforth and Kaurah, 1992].
Nasal polypi, proptosis, nasal discharge, mucin cast, Telecanthus
and facial asymmetry were seen in our patients.
As many as 42% of pediatric patients present with alteration of their facial skeletons (proptosis, telecanthus
, or malar flattening) compared to 10% for adults, which may be explained by the more pliable bony structure of children) Notably, as many as 70% of pediatric patients present with unilateral disease, while 63% of adults present with bilateral disease.