tegaserod


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tegaserod

a 5-HT4 receptor partial agonist used to treat irritable bowel syndrome when the primary bowel symptom is constipation.
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In clinical trials, tegaserod maleate (Zelnorm) was effective in about 40% of patients.
It is interesting to note that also with recently developed more targeted drugs like tegaserod (Mertz, 2003), alosetron (SCRIP, 2000) or cilansetron (Pink Sheet, 2004) versus placebo response rates cover the same range (52/42%, 41/29%, 60/45%).
El tegaserod es un agonista parcial selectivo de los receptores de 5-hidroxitritamina-4 (5-HT4), sin afinidad significativa por otros receptores.
Asimismo, se presentaron en la publicacion evidencias clinicas de que el farmaco Tegaserod es efectivo para el control del SII en grado A, ya que alivia los multiples sintomas de dolor y distension abdominal y estrenimiento.
4]-receptor agonist tegaserod was shown to be effective in women with IBS-C, both in relieving constipation and in reducing pain.
MUNICH -- Results of a large case-control study suggest the irritable bowel syndrome drug tegaserod (Zelnorm) may have gotten a bum deal when the Food and Drug Administration suspended its marketing in March 2007 because of cardiovascular concerns.
Tegaserod sales were halted when a Novartis review of more than 18,000 patients in its database turned up 13 cardiac is chemic events in 11,614 treated patients, compared with just 1 case in 7,031 placebotreated controls, explained Dr.
There are seven types of products that act as laxatives: saline (phosphates and magnesium hydroxide and its salts), stimulants/irritants (cascara, bisacody1, casanthranol, senna, and castor oil), bulking agents (methylcellulose, polycarbophil, and psyllium), emollient (mineral oil), fecal softeners (docusate), hyperosmotics (glycerin, lactulose), and tegaserod (Zelnorm).
Tegaserod, approved in 2002 for constipation-predominant irritable bowel syndrome in women, was recently approved by the Food and Drug Administration for treating chronic idiopathic constipation in women and men younger than 65.
Gracias a los avances en la medicina, ya existen farmacos eficaces para controlar las molestias de la colitis, como Tegaserod, el cual ha demostrado superioridad en el control del dolor o malestar abdominal, el estrenimiento y la distension abdominal.
The partial 5-HT4-receptor agonist tegaserod was shown to be effective in women with IBS-C, both in relieving constipation and in reducing pain.