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the quantity to be administered at one time, as a specified amount of medication or a given quantity of radiation.
absorbed dose that amount of energy from ionizing radiations absorbed per unit mass of matter, expressed in rads.
air dose the intensity of an x-ray or gamma-ray beam in air, expressed in roentgens.
booster dose an amount of immunogen (vaccine, toxoid, or other antigen preparation), usually smaller than the original amount, injected at an appropriate interval after primary immunization to sustain the immune response to that immunogen.
curative dose (CD) a dose that is sufficient to restore normal health. See also median curative dose.
divided dose fractionated dose.
effective dose (ED) that quantity of a drug that will produce the effects for which it is administered. See also median effective dose.
erythema dose that amount of radiation that, when applied to the skin, causes erythema (temporary reddening).
fatal dose lethal dose.
fractionated dose a fraction of the total dose prescribed, as of chemotherapy or radiation therapy, to be given at intervals, usually during a 24-hour period.
infective dose (ID) that amount of a pathogenic agent that will cause infection in susceptible subjects. See also median infective dose and tissue culture infective dose.
lethal dose (LD) that quantity of an agent that will or may be sufficient to cause death. See also median lethal dose and minimum lethal dose.
loading dose a dose of medication, often larger than subsequent doses, administered for the purpose of establishing a therapeutic level of the medication.
maintenance dose the amount of a medication administered to maintain a desired level of the medication in the blood.
maximum tolerated dose tolerance dose.
maximum permissible dose the largest amount of ionizing radiation that one may safely receive within a specified period according to recommended limits in current radiation protection guides. The specific amounts vary with age and circumstance.
median curative dose (CD50) a dose that abolishes symptoms in 50 per cent of test subjects.
median effective dose (ED50) a dose that produces the desired effect in 50 per cent of a population.
median infective dose (ID50) that amount of pathogenic microorganisms that will produce demonstrable infection in 50 per cent of the test subjects.
median lethal dose (LD50) the quantity of an agent that will kill 50 per cent of the test subjects; in radiology, the amount of radiation that will kill, within a specified period, 50 per cent of individuals in a large group or population.
median tissue culture infective dose (TCID50) that amount of a pathogenic agent that will produce infection in 50 per cent of cell cultures inoculated.
minimum lethal dose
1. the amount of toxin that will just kill an experimental animal.
2. the smallest quantity of diphtheria toxin that will kill a guinea pig of 250-gm weight in 4 to 5 days when injected subcutaneously.
reference dose an estimate of the daily exposure to a substance for humans that is assumed to be without appreciable risk; it is calculated using the no observed adverse effect level and is more conservative than the older margin of safety.
skin dose (SD)
1. the air dose of radiation at the skin surface, comprising the primary radiation plus backscatter.
2. the absorbed dose in the skin.
threshold dose the minimum dose of ionizing radiation, a chemical, or a drug that will produce a detectable degree of any given effect.
threshold erythema dose (TED) the single skin dose that will produce, in 80 per cent of those tested, a faint but definite erythema within 30 days, and in the other 20 per cent, no visible reaction.
tissue culture infective dose (TCID) that amount of a pathogenic agent that will produce infection when inoculated on tissue cultures; used with a numeric qualifier.
tolerance dose the largest quantity of an agent that may be administered without harm. Called also maximum tolerated dose.
Miller-Keane Encyclopedia and Dictionary of Medicine, Nursing, and Allied Health, Seventh Edition. © 2003 by Saunders, an imprint of Elsevier, Inc. All rights reserved.
References in periodicals archive ?
In the test two models of TED were mounted under supervision of Jack Forrester from the National Oceanic and Atmospheric Administration (NOAA) performed during a visit to Itajai in September 2013.
A TED with a double flap opening aiming downwards: installed on the trawl to allow the organisms to escape below the net, i.e., escape opening has 176 cm long and 53 cm wide and is located at net bottom.
"Teds Jo will have a trial at Hall Green next weekend, but I'm sure he'll run the track well.
Teds Jo (T5) proved an emphatic winner at Walthamstow
Heppell's forecast rests on the assumption that TEDs reduce the mortality rate of net-trapped juvenile loggerheads by only 34 percent each year, because these smaller turtles sometimes get swept between the bars of the devices and become caught in the nets.
"TEDs have had a very positive effect on increasing the population [of loggerhead turtles]," Heppell says, "but 70 years is a longer time to see a 10-fold population recovery than we'd expected." She adds that although the number of nesting loggerheads has increased within the past three years, indicating the overall benefits of TEDs, "we have to be a little cautious in saying we've found the answer to saving the [loggerhead) turtle population....
As the title suggests, Ted and Robin would watch the sunrise together.
Now, where is Barney, and what's on his mind when he decides to sneak out of Ted's room?
Invariably starting "I was walking down the road the other day...", Ted's jokes were zen-like nuggets of pathos, dressed up as nonchalance, with a sting in the tail.
Aside from his endearing spoof of "Star Trek" and its fan base, Parisot has also directed episodes of "Curb Your Enthusiasm," "Monk," and "Modern Family." A resume like that is a perfect fit for the "Bill and Ted" franchise.