technetium Tc 99m sestamibi


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technetium Tc 99m sestamibi

A radioactive tracer consisting of technetium-99m linked to sestamibi. It is used to image blood flow to the heart muscle, esp. when combined with exercise or pharmacological “stress” tests. In a heart with normal blood flow, the isotope should be taken up uniformly throughout the heart muscle. Decreased uptake by regions of the heart occurs when coronary artery blood flow to those regions is blocked, e.g., by atherosclerotic plaque. Synonym: sestamibi
See also: technetium-99m
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Presence of concomitant thyroid nodules is very common and can lead to both false-negative and false positive results of technetium Tc 99m sestamibi scan.
1] Recently there has been increased interest in using thallium Tl 201 and technetium Tc 99m sestamibi to assess patients with coronary artery disease.