If approved, IDP-123 will be the first tazarotene
acne treatment available in a lotion form.
Safety and efficacy of a fixed combination halobetasol and tazarotene
lotion in the treatment of moderate-to-severe plaque psoriasis: a pooled analysis of two phase 3 studies.
"The DUOBRII formulation brings together two well-known ingredients in a unique lotion vehicle with low concentrations of halobetasol propionate and tazarotene
, into a single, first-of-its-kind topical treatment.
causes more dryness and irritation, so I prescribe it less often than tretinoin.
Target: Dermatology products, including Aczone (dapsone), Tazorac (tazarotene
), Azelex (azelaic acid) and Cordran Tape (flurandrenolide)
For limited but significant involvement, treatments include topical retinoids, such as tretinoin or tazarotene
, topical or intralesional corticosteroids, emollients, imiquimod cream, laser ablation, and cryotherapy.
is the most commonly used retinoid for topical treatment [167-169] and is usually used in combination with phototherapy, corticosteroids, vitamin D, and other treatments [170-172].
(6) Other treatment options with reported success include oral isotretinoin and topical retinoids, including tretinoin gel and tazarotene
The topical treatment includes benzoyl peroxide (2.5-10%), topical retinoids (tretinoin, isotretinoin, adapalene, tazarotene
, etc.), topical antibiotics (erythromycin, clindamycin, etc.), and other topical agents such as salicylic acid and azelaic acid.
The treatment of EPS primarily consists of oral isotretinoin, intralesional injections of triamcinolone acetonide, topical application of tazarotene
or allium cepa-allantoin-pentaglycan gel or cryotherapy.
(1,11,12,13,14) Silver nitrate, phenol, and trichloracetic acid are used as chemical agents, while treatment options for immunocompromised patients with refractory lesions include topical cidofovir (5%), intralesional or systemic interferon, imiquimod cream (5%), salicylic acid, glycolic acid, tretinoin, tazarotene
, 5% sodium nitrate, podophyllotoxin, liquefied phenol, cantharidin, potassium hydroxide, 1% adenine cream, and oral cimetidine.
Three topical retinoids are approved for use in the United States: tretinoin, adapalene, and tazarotene
. Adapalene is available by prescription, 0.1% and 0.3% gel, and over the counter, 0.1% gel (Differin Gel) (table 2).