taxoid

Member of a class of anticancer drugs derived from yew tree products, including paclitaxel and docetaxel.

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Romieu et al., "Phase II multicenter study of larotaxel (XRP9881), a novel taxoid, in patients with metastatic breast cancer who previously received taxane-based therapy," Annals of Oncology, vol.

Phytochemicals and Biogenic Metallic Nanoparticles as Anticancer Agents

Rowehl et al., "Prostate cancer stem cell-targeted efficacy of a new-generation taxoid, SBT-1214 and novel polyenolic zinc-binding curcuminoid, CMC2.24," PLoS ONE, vol.

A novel chemically modified curcumin reduces severity of experimental periodontal disease in rats: initial observations

Wilson et al., "High throughput sequencing technology reveals that the taxoid elicitor methyl jasmonate regulates microRNA expression in Chinese yew (Taxus chinensis)," Gene, vol.

Discovery of novel leaf rust responsive microRNAs in wheat and prediction of their target genes

Molecular cloning and characterization of a cytochrome P450 taxoid 2a-hydroxylase involved in Taxol biosynthesis.

Una revision sobre la produccion de taxoides anticancerigenos en cultivos in vitro de callos y celulas de Taxus spp

They attributed the ONJ event as being secondary to taxoid classification chemotherapy drugs (Taxol, Taxotere) used in cancer treatment.

Bisphosphonate-associated osteonecrosis of the jaw: A literature review and clinical practice guidelines

Tokyo, Japan, Aug 22, 2005 - (JCNN) - Aventis Pharma of the sanofi-aventis Group announced on August 19 that it has obtained additional approval for TAXOTERE Injection, its proprietary taxoid antitumor agent, from the Ministry of Health, Labor and Welfare as of August 18.

Aventis Pharma Obtains Additional Approval for Taxoid Antitumor Agent TAXOTERE Injection

Taxotere, like other taxoid drugs, inhibits cancer cell division by disrupting tubulin--the scaffolding in cells which leads to phosphorylation and inactivation of Bcl-2, a protein expressed by 60%-90% of hormone-refractory prostate cancer specimens that interferes with apoptosis.

Taxotere (with prednisone)

Taxotere, like other taxoid drugs, inhibits cancer cell division by disrupting tubulin--the scaffolding in cells--which leads to phosphorylation and inactivation of Bcl-2, a protein expressed by 60%-90% of hormone-refractory prostate cancer specimens that interferes with apoptosis.

Taxotere (with prednisone)

Up to now, microtubule toxin based ADCs from Creative Biolabs have been used in clinical treatment considering the potential side effects, especially toxic moieties, including auristatins, epothilone, maytansinoids, taxoids, tubulysins, and vinorelbine.

Creative Biolabs Provides Customized Payload Services for Antibody-drug Conjugate

General and recent aspects of the chemistry and structure-activity relationships of taxoids. Curr.

Salvianolic acid A reverses paclitaxel resistance in human breast cancer MCF-7 cells via targeting the expression of transgelin 2 and attenuating PI3 K/Akt pathway

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