"Wake-promoting neurons (WPNs) are extremely vulnerable to AD but not to 4 repeat tauopathies
," the researchers wrote about their findings.
Axon Neuroscience SE, a global company involved in the development of tau-immunotherapies and diagnostics for Alzheimer's disease and other tauopathies
, announced yesterday that it has named Michal Fresser as the new chief executive officer of Axon Group.
ACI-35.030 targets pathological Tau and is intended as a disease-modifying treatment for Alzheimer's disease (AD) and other Tauopathies
ACI-35.030 targets pathological Tau and is intended as a disease-modifying treatment for Alzheimer's disease and other Tauopathies
. By targeting specific pathological forms of Tau protein, immunization with anti-Tau vaccines has become an important strategy for the treatment of AD and other Tauopathies
because it has the potential to prevent and reduce the development and spread of Tau pathology throughout the brain.
Regenxbio Inc (NASDAQ: RGNX) and Swiss biotech Neurimmune announced an exclusive license development and commercialization agreement to discover and develop AAV gene therapies using NAV Vectors to deliver human antibodies against targets implicated in chronic neurodegenerative diseases, including tauopathies
E2814 is being developed as a disease modifying agent for Alzheimer's disease and other tauopathies
, Phase I clinical studies are under preparation.
Sangamo is also developing ZFP-TFs to down-regulate the expression of tau, a protein associated with Alzheimer's disease and other tauopathies
Assesment of serum uric acid as risk factor for tauopathies
. J Neural Transm 2017;124:1105-1108.
Tau pathology is strongly linked to the progression of several neurodegenerative diseases, called tauopathies
, including Alzheimer's disease.
Alzheimer's is part of a group of conditions known as tauopathies
. Ann Rev Neurosci 2001;24:1121-59.
The PET imaging tracer has the potential to visualise tau pathology in diverse tauopathies
, including Mild Cognitive Impairment (MCI), dementia due to Alzheimer's disease (AD), Corticobasal Degeneration Syndrome (CBS) and Progressive Supranuclear Palsy (PSP).