targeted therapy


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targeted therapy

A generic term for therapies that impact on a specific molecular pathway, target or ligand.

Examples
Gefitimib for non-small cell carcinoma of the lungs with mutations in epidermal growth factor receptor, and imatinib for GIST tumours with activating mutations in c-Kit.
References in periodicals archive ?
The oral cancer therapeutics market analysis considers sales from both targeted therapy and chemotherapy.
For example, tumor genetics can identify whether the patients are bearing targetable driver oncogene mutations and thus segregate patients into various chemo- and targeted therapy regimens, said Dr.
This is the factor that will make targeted therapy more effective than the traditional treatments.
With the latest advance in targeted therapy, the US Massachusetts General Hospital has discovered a new drug that targets the actual gene which drives as much as 25% of treatment resistance.
"This is the first study to show improved survival for any targeted therapy when used with endocrine therapy as a first-line treatment for advanced breast cancer," lead author Dr Hurvitz said.
It has the potential to discover previously uncharacterized events, which is important when identifying patients who could have strong response to targeted therapy.
[USA], Apr 7 (ANI): Breast cancer patients who do not respond to targeted therapy show epigenetic differences, a new study has revealed.
Based on therapy type, global anticancer drugs market is segmented into chemotherapy, targeted therapy, immunotherapy and others.
Because of the type of cancer she has, Elkins was able to be treated with a targeted therapy oral medication to address the mutation and shrink her tumor.
Specific topics include pharmacogenomics and the role of genomics in cancer therapeutics, alkylating and methylating agents, targeted therapy in non-small cell lung cancer, the endocrine therapy of breast cancer, and hematopoietic growth factors.
It also demonstrates Novartis leadership in BRAF+ targeted therapy, and to date, more than 60,000 patients worldwide have been treated with the combination therapy across four indications.
(1) If targeted therapy is provided within a few hours of patient presentation, the progression of a bloodstream infection to sepsis can be prevented, reducing the likelihood of health consequences that are always significant and often fatal.

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