target lesion


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target lesion

Dermatology A lesion typical of erythema multiforme–EM in which a vesicle is surrounded by an often hemorrhagic maculopapule; EM is often self-limited, of acute onset, resolves in 3-6 wks, and has a cyclical pattern; EM lesions are 'multiform' and include macules, papules, vesicles, bullae Etiology Idiopathic or follow infections, drug therapy or occur in immunocompromised hosts

target lesion

characteristic skin lesion of erythema multiforme

lesion

any pathological or traumatic discontinuity of tissue or loss of function of a part. Lesion is a broad term, including wounds, sores, ulcers, tumors, cataracts and any other tissue damage. They range from the skin sores associated with eczema to the changes in lung tissue that occur in tuberculosis.
Enlarge picture
Terms describing distribution of lesions. By permission from Slauson DO, Cooper BJ, Mechanisms of Disease: A Textbook of Comparative General Pathology, Mosby, 2001

target lesion
see target lesion.

target

1. an object or area toward which something is directed, e.g. target animal, population, level or nucleotide sequence.
2. the area of the anode of an x-ray tube where the electron beam collides causing the emission of x-rays.
3. a cell or organ that is affected by a particular agent, e.g. a hormone or drug.

target cell
see target cell.
target-film distance
the distance from the target of the x-ray tube and the plane of the x-ray film.
target lesion
skin lesion consisting of annular or arciform areas of erythema with central pigmentation. Associated with bacterial hypersensitivity and seborrheic dermatitis. Called also bull's eye lesion.
performance target
in herd health programs target performances are set up in a number of production and health functions in order to provide an incentive and give some measure of performance other than an absolute one. This enables farmers to be rated on their effective performance in spite of the great variations that can occur between them in basic resources.
References in periodicals archive ?
Additionally, a tough fascial layer may exist between the skin entry site and the target lesion that can be traversed once with the introducer to avoid having to cross this tough tissue multiple times with the biopsy needle.
Response of bystander lesions was highly correlated with outcome in treated target lesions, with a bystander lesion OR of 61% in subjects achieving complete or partial response in their target lesions versus 18% bystander lesion OR in subjects that did not achieve this level or response in their target lesions;
Primary safety endpoint was freedom from a composite of all death, clinically driven target lesion revascularization (TLR), or any amputation of the index limb at 30 (+7 days) and was compared to a performance goal (PG) of 88%.
Secondary endpoints include all-cause and cardiac mortality, myocardial infarction, Major Adverse Cardiac Event (MACE) and stent thrombosis rates at 30 days, nine months and one through five years, as well as clinically driven Target Lesion Revascularization (TLR), Target Vessel Revascularization (TVR) and Target Lesion Failure (TLF) rates at the same follow-up times.
A large difference in the rates of target lesion revascularization (4.
The primary endpoint was six-month major adverse coronary events (MACE) defined as a composite of cardiac death, clinically driven target lesion revascularization (TLR) and myocardial infarction.
The primary endpoint is a composite measure of cardiac death, heart attack (target vessel myocardial infarction) and target lesion revascularization (repeat procedures on the treated vessel) at one year.
The need for target lesion revascularization was 75% lower in subjects who received sirolimus-coated stents (3.
The device is based on the highly deliverable Pantera semicompliant balloon, which is then coated with a matrix of proven antiproliferative paclitaxel and the biocompatible butyryl-tri-hexyl citrate (BTHC) excipient--enabling an optimal drug transfer to the target lesion tissue.
We also saw that the Genous Stent tended to have fewer episodes of target lesion revascularization between one and two years.
The MACE rates include any deaths, myocardial infarctions and target lesion revascularization within the 30-day period.
Assessed at 12 months, clinical endpoints for RESOLUTE Japan included target lesion failure (TLF) - a composite endpoint of cardiac death, target vessel myocardial infarction (MI) and clinically driven target lesion revascularization (TLR) - and stent thrombosis.