tangeretin

tangeretin

A polymethoxyflavone (bioflavonoid) found in citrus fruits, which has multiple claimed health benefits. Tangeretin can induce apoptosis (programmed cell death) in Bcr-Abl+ cells via cell cycle arrest by inducing the unfolded protein response, and has synergistic cytotoxicity with imatinib.
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Meanwhile, oranges are rich in several antioxidants, including hesperidin, naringin and tangeretin, which studies show may help to lower blood cholesterol.
25 simple ways to GET MORE FROM YOUR 5-A-DAY for free! Your fruit and veg doesn't have to be organic - and costly - to be good for you. Dietitian Juliette Kellow reveals top tricks to make them work harder without spending more
The present study was designed to evaluate the antihyperglycemic potential of tangeretin on the activities of key enzymes of carbohydrate and glycogen metabolism in control and streptozotocin induced diabetic rats.
Effect of tangeretin, a polymethoxylated flavone on glucose metabolism in streptozotocin-induced diabetic rats
In a clinical trial measuring the serum bioavailability of Sytrinol, softgels manufactured by SGTI exhibited enhanced bioavailability of the key active ingredients--specifically, the two polymethoxylated flavones tangeretin and nobiletin--compared to powder-filled, two-piece hard shell capsules.
Soft Gel Technologies to manufacture Sytrinol softgels
In addition, an extract including nobiletin and tangeretin (4',5,6,7,8-pentamethoxyflavone) has been reported to show antimicrobial activity [51].
Beneficial actions of citrus polymethoxy flavonoids in treating acne
The early studies involving orange juice have identified that heptamethoxyflavone (HMF), tangeretin, and nobiletin are not only substrates for both P-glycoprotein and OATP, but also are inhibitors that decrease the bioavailability significantly of other substrates, such as fexofenadine.
Effect of orange juice on bioavailability of levofloxacin
Lamson and Brignall (1999) have another specific concern regarding the use of tangeretin and tamoxifen.
The antioxidant controversy in cancer care
2000) also showed that [less than or equal to] 25 [micro]M concentrations of various phytochemicals block TCDD-induced transformation of rat liver cytosolic AhR, and these include chrysin, baicalein, apigenin, luteolin, tangeretin, galangin, kaempferol, fisetin, morin, quercetin, myricetin, tamarixetin, isorhamnetin, naringenin, eriodictyol, and hesperitin.
Flavonoids as aryl hydrocarbon receptor agonists/antagonists: effects of structure and cell context
Individually, the best performers against both types of cells were tangeretin and nobiletin, a pair of flavonoids from tangerines.
Juicy anticancer prospects
Buffalo found that tangeretin, quercetin, and nobiletin
HEALTH BENEFITS OF CITRUS FRUIT EXPANDS; NEW RESEARCH FINDINGS COMPELLING
Regulation of adipocytokine secretion and adipocyte hypertrophy by polymethoxyflavonoids nobiletin and tangeretin.
Suppression of adipocyte hypertrophy by polymethoxyflavonoids isolated from Kaempferia parviflora
In a clinical trial, soft gels exhibited enhanced bioavailability of the key active ingredients found in Sytrinol--the polymethoxylated flavones tangeretin and nobiletin.
The heart health market: a strong pulse: the conversation about cardiovascular disease has become more complex, and new opportunities are opening for nutraceuticals
Tangeretin, a citrus flavonoid, inhibits PGDF-BB-induced proliferation and migration of aortic smooth muscle cells by blocking AKT activation.
Flavonoids promoting HaCat migration: II. Molecular mechanism of 4',6,7-trimethoxyisoflavone via NOX2 activation

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