tangeretin

tangeretin

A polymethoxyflavone (bioflavonoid) found in citrus fruits, which has multiple claimed health benefits. Tangeretin can induce apoptosis (programmed cell death) in Bcr-Abl+ cells via cell cycle arrest by inducing the unfolded protein response, and has synergistic cytotoxicity with imatinib.
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Indeed, citrus fruits are proposed as anti-atherosclerotic agents because they are rich in flavonoids such as nobiletin, naringin, tangeretin and hesperetin.
2011), flavonoids such as hesperidin, ferulic acid, tangeretin, sinensetin, nobiletin (Malterud and Rydland 2000; Luo et al.
Meanwhile, oranges are rich in several antioxidants, including hesperidin, naringin and tangeretin, which studies show may help to lower blood cholesterol.
In a clinical trial measuring the serum bioavailability of Sytrinol, softgels manufactured by SGTI exhibited enhanced bioavailability of the key active ingredients--specifically, the two polymethoxylated flavones tangeretin and nobiletin--compared to powder-filled, two-piece hard shell capsules.
Plus, orange peels are rich in tangeretin and nobiletin - flavonoids that boast anticancer, antidiabetic and anti-inflammatory properties.
In addition, an extract including nobiletin and tangeretin (4',5,6,7,8-pentamethoxyflavone) has been reported to show antimicrobial activity [51].
The early studies involving orange juice have identified that heptamethoxyflavone (HMF), tangeretin, and nobiletin are not only substrates for both P-glycoprotein and OATP, but also are inhibitors that decrease the bioavailability significantly of other substrates, such as fexofenadine.
Flavones Tangeretin Parsley, Celery, Capsicum Heptamethoxyflavone pepper.
Lamson and Brignall (1999) have another specific concern regarding the use of tangeretin and tamoxifen.
2000) also showed that [less than or equal to] 25 [micro]M concentrations of various phytochemicals block TCDD-induced transformation of rat liver cytosolic AhR, and these include chrysin, baicalein, apigenin, luteolin, tangeretin, galangin, kaempferol, fisetin, morin, quercetin, myricetin, tamarixetin, isorhamnetin, naringenin, eriodictyol, and hesperitin.
For example, the flavonoid tangeretin is known to be a potent inhibitor of tumor cell growth.