tangeretin

tangeretin

A polymethoxyflavone (bioflavonoid) found in citrus fruits, which has multiple claimed health benefits. Tangeretin can induce apoptosis (programmed cell death) in Bcr-Abl+ cells via cell cycle arrest by inducing the unfolded protein response, and has synergistic cytotoxicity with imatinib.
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[6.] Pan MH, Chen WJ, Lin-Shiau SY Ho CT Lin JK, Tangeretin induces cell-cycle GI arrest through inhibiting cyclin-dependent kinases 2 and 4 activities as well as elevating Cdk inhibitors p21 and p27 in human colorectal carcinoma cells, Carcinogenesis 2002; 23: 1677-84, [CrossRef]
Investigation of the Anticancer Mechanism of isoorientin isolated from Eremurus SpectabHis Leaves via Cell Cycle Pathways in HT-29 Human Colorectal Adenocarcinoma Cells
The major bioflavonoids found in citrus fruits are diosmin, diosmetin, hesperidin, hesperetin, naringin, naringenin, narirutin, neohesperidin, nobiletin, tangeretin, eriodictyol, and eriocitrin.
Citrus Bioflavonoids: Synergy with Vitamin C & Beyond: The health benefits of flavonoids have been evaluated and validated in numerous scientific studies
Release of naringin, tangeretin, ferulic acid, p-coumaric acid, and gallic acid was enhanced.
Quality Characteristics and Antioxidant Activities of Rice/Adzuki Bean Mixtures Cooked Using Two Different Methods
[18] used a HPLC-PDA method to identify 8 components (rutin, narirutin, naringin, hesperidin, neohesperidin, poncirin, nobiletin, and tangeretin) in FA, but this method was unreasonably time-consuming (60 min).
Development of an Ultra-High Performance Liquid Chromatography Method for Simultaneous Determination of Six Active Compounds in Fructus aurantii and Rat Plasma and Its Application to a Comparative Pharmacokinetic Study in Rats Administered with Different Doses
Arafa, "Tangeretin alleviates cisplatin-induced acute hepatic injury in rats: targeting MAPKs and apoptosis," PLoS One, vol.
Protective Effect of Sika Deer (Cervus nippon) Velvet Antler Extract against Cisplatin-Induced Kidney and Liver Injury in a Prostate Cancer PC-3 Cell Xenograft Model
In this study, we assessed the anti-asthmatic effects of tangeretin, an O-polymethoxylated flavone found in tangerine and other citrus fruits.
Tangeretin has anti-asthmatic effects via regulating PI3K and Notch signaling and modulating Th1/Th2/ Th17 cytokine balance in neonatal asthmatic mice
Kuo, "Hesperidin, nobiletin, and tangeretin are collectively responsible for the anti-neuroinflammatory capacity of tangerine peel (Citri reticulatae pericarpium)," Food and Chemical Toxicology, vol.
Infrared Drying as a Quick Preparation Method for Dried Tangerine Peel
Habtemariam et al., "Neuroprotective effects of citrus fruit-derived flavonoids, nobiletin and tangeretin in alzheimer's and parkinson's disease," CNS and Neurological Disorders Drug Targets, 2017.
Preparation and Characterisation of Nobiletin-Loaded Nanostructured Lipid Carriers
Kim, "Anti-inflammatory and antioxidant mechanism of tangeretin in activated microglia," Journal of Neuroimmune Pharmacology, vol.
Kiwifruit Alleviates Learning and Memory Deficits Induced by Pb through Antioxidation and Inhibition of Microglia Activation In Vitro and In Vivo
Hwang, "Tangeretin stimulates glucose uptake via regulation of AMPK signaling pathways in C2C12 myotubes and improves glucose tolerance in high-fat diet-induced obese mice," Molecular and Cellular Endocrinology, vol.
Spatholobus suberectus Exhibits Antidiabetic Activity In Vitro and In Vivo through Activation of AKT-AMPK Pathway
Indeed, citrus fruits are proposed as anti-atherosclerotic agents because they are rich in flavonoids such as nobiletin, naringin, tangeretin and hesperetin.
Anti-atherosclerotic plants which modulate the phenotype of vascular smooth muscle cells
2005) such as -pinene (Azar et al., 2011), flavonoids such as hesperidin, ferulic acid, tangeretin, sinensetin, nobiletin (Malterud and Rydland 2000; Luo et al.
SELECTED PLASMA CONSTITUENTS OF BROILER CHICKENS FED DIFFERENT LEVELS OF DRIED SWEET ORANGE (CITRUS SINENSIS) PEELS

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