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tamoxifen/ta·mox·i·fen/ (tah-mok´sĭ-fen) a nonsteroidal antiestrogen used as the citrate salt in the prophylaxis and treatment of breast cancer.
tamoxifenAdjuvant tamoxifen, Novaldex® Oncology A nonsteroidal anti-estrogenic used to treat early estrogen receptor–ER-positive breast CA; prophylactic tamoxifen may used in postmenopausal ♀ at high risk for breast CA Other benefits ↓ Serum lipids, ↓ risk of CAD; it maintains bone mass and ↓ osteoporosis Cons ↑ risk of endometrial CA. See Breast cancer, Chemokine, STAR. Cf Raloxifene.
tamoxifenA drug that blocks oestrogen receptors and is useful in the treatment of certain cancers, especially breast cancer. Research involving 37,000 women has shown that tamoxifen substantially improves the survival figures after breast cancer and substantially reduces the probability of cancer in the other breast. The drug also stimulates egg production from the ovaries and can be used to treat infertility. It is on the WHO official list. Brand names are Nolvadex and Tamofen.
tamoxifenhormone antagonist used to treat/prevent breast cancer; patients on tamoxifen are prone to thromboembolism, especially postsurgery or following prolonged rest
Patient discussion about tamoxifen
Q. Hot flashes while on tamoxifen - is there anything to do? Hello, Last year I was diagnosed with breast cancer, and after surgery and radiation, I was given tamoxifene. In the beginning it was OK, but now I have hot flashes. Usually I can to hold my self until It passes, but some times (like during work) it’s just so bothering- is there anything I can do to make these flashes go?
Q. I heard about tamoxifen. Should women who have an increased risk of breast cancer take tamoxifen?
Q. Want to know how this tamoxifen works to fight cancer as my lump is removed and is there any side effects? Hi… I am 26 years lady, my breast cancer lump is removed and after my chemo I am on tamoxifen now……wanted to know how this tamoxifen works to fight cancer as my lump is removed now and is there any side effects associated with it?