tachykinin


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Related to tachykinin: tachykinin 2, neurokinin 2

tach·y·ki·nin

(tak'i-kī'nin),
Any member of a group of polypeptides, widely scattered in vertebrate and invertebrate tissues, which have in common four of the five terminal amino acids: Phe-Xaa-Gly-Leu-Met-NH2; pharmacologically, they all cause hypotension in mammals, contraction of gut and bladder smooth muscle, and secretion of saliva.
[G. tachys, swift, + kineō, to move, + -in]

tachykinin

/tachy·ki·nin/ (-ki´nin) any of a family of peptides structurally and functionally similar to substance P; all are potent, rapidly acting secretagogues and cause smooth muscle contraction and vasodilation.

tachykinin

tachykinin

(tăk″kī′nĭn) [″ + ″],

TK

Any of a large family of peptides that function as neurotransmitters in the central and peripheral nervous systems. They have extraneuronal activity in other body tissues. Their diverse biological actions are mediated through cellular G proteins.
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References in periodicals archive ?
Effects of central administration of tachykinin receptor agonists and antagonists on plus-maze behavior in mice.
The pharmacology of GR203040, a novel, potent and selective non-peptide tachykinin NK1 receptor antagonist.
2]) induces a decrease in calcitonin gene-related peptide (CGRP) and tachykinin immunoreactivity in guinea-pig peripheral airways.
Further evidence for the involvement of tachykinin receptor subtypes in formalin and capsaicin models of pain in mice.
Substance P (SP), a neuropeptide and member of the tachykinin family, has potent effects on airway smooth muscle tone, vascular permeability, and mucus secretion (Barnes et al.
Tachykinin peptides, receptors, and peptidases in airway disease.
Tachykinin NK1 and receptor-mediated control of peristaltic propulsion in the guinea-pig small intestine in vivo.