We report this data for 2 subgroups according to left ventricular ejection fraction (LVEF) test result, to differentiate systolic heart failure
from diastolic and unclassified heart failure.
Beta-blockers have been shown to improve survival, reduce hospitalizations and improve the strength and size of the heart in patients with systolic heart failure
Caption: In systolic heart failure
(pictured), the left ventricle becomes enlarged and contracts weakly, impeding bloodflow from the heart to the body.
A 58-year-old man with chronic systolic heart failure
and type 2 diabetes mellitus presented with bacteremia, acute exacerbation of chronic heart failure, and acute renal failure.
Relation of reduced expression of MiR-150 in platelets to atrial fibrillation in patients with chronic systolic heart failure
When I was in medical school, the dogma was to never give beta-blockers to patients with systolic heart failure
, because it would worsen the heart failure.
In systolic heart failure
, the left ventricle, which pumps oxygenated blood to tissues throughout your body, becomes enlarged and cannot contract strongly enough to push out a sufficient amount of blood.
In contrast, heart failure and a reduced EF have been termed systolic heart failure
Thus, there appears to be an entire spectrum of systolic function abnormalities, ranging from normal systolic heart function to systolic heart failure
, with heart failure with normal EF being located in between.
The new drug application is based on global clinical trial results from the large, multi-centre, randomised, double-blind, placebo-controlled, outcomes Phase III Systolic Heart failure
treatment with the If inhibitor ivabradine Trial.
Suggestions for the treatment ofchronic systolic heart failure
Objective: Systolic heart failure
is a chronic condition with significant morbidity and mortality.