Caption: Figure 3: Transaortic Doppler at 30 days after TAVI reveals mean systolic gradient
of 12mmHg and no aortic insufficiency.
carried out a multicenter study including 211 patients of which 172 were <1 year of age; 88% of these patients achieved a reduction in their systolic gradient
to ≤25 mmHg.
[10.] Stephan PJ, Henry AC, Hebeler RF Jr, Whiddon L, Roberts WC: Comparison of age, gender, number of aortic valve cusps, concomitant coronary artery bypass grafting, and magnitude of left ventricular systemic arterial peak systolic gradient
in adults having aortic valve replacement for isolated aortic stenosis.
Aortic stenosis was defined as follows: mild (aortic jet velocity of 2.0-2.9 m/s and a peak systolic gradient
and a mean gradient of <36 mmHg and <20 mmHg, resp.), moderate (aortic jet velocity of 3.0-4.0 m/s and a peak systolic gradient
and a mean gradient of 36-64 mmHg and 20-40 mmHg, resp.), and severe (aortic jet velocity of >4 m/s and a peak systolic gradient
and a mean gradient of >64 mmHg and >40 mmHg, resp.).
Average pre-procedure systolic gradient
across PV fell from 93 + 35 mmHg to 29 + 20 mmHg with mean percentage reduction of 67.2 + 19.8%.
Inclusion criteria were patients aged between 18 months and 18 years with significant coarctation of the aorta and transcatheter systolic gradient
In the preceding equations V2: maximum pulmonary valve velocity (m/sec), V1: subvalvular pulmonary velocity (m/sec), and RV-RA gradient systolic gradient
between RA and RV (mm Hg).
A Doppler study with transthoracic echocardiogram showed the RVOT to have a systolic gradient
of 60 mmHg and was the most probable source of the murmur.
Continuous wave Doppler showed flow across the membrane with a peak diastolic gradient of 6 mmHg, peak systolic gradient
of 2 mmHg, and a mean of 4 mmHg (Figure 2).
No intraventricular systolic gradient
was detected at rest and with Valsalva maneuver.
The peak systolic gradient
was measured invasively before stent implantation.
The decrease in mean peak-to peak systolic gradient
from 37.5 to 7.2 mmHg was statistically significant (p<0.001, Wilcoxon signed ranks test) Mean narrowest diameter at coarctation site increased in all patients from 6.4 to 11.4 mm, which was statistically significant (p<0.001, Wilcoxon signed ranks test).