To put the potential impact of the findings into context, Juraschek says, the FDA requires any new antihypertensive agent submitted for approval to lower systolic blood pressure
by 3-4 mm Hg.
gov/pubmed/15752957) associated with systolic blood pressure
that is about 2.
Interpretation: Treating to a lower systolic blood pressure
goal of less than 120 mmHg may provide added benefit for patients who meet the study population criteria, but with potential risks.
One trial in the review (ACCORD, 4734 patients) compared outcomes from significantly lower and standard systolic blood pressures
(119/64 mm Hg vs 134/71 mm Hg; P<.
Esmolol 50 mg group adequately attenuated the heart rate but the systolic blood pressure
and diastolic blood pressure were not satisfactorily attenuated compared to esmolol 100 mg group.
The systolic blood pressure
differences we found are small for the individual, but they are important at the population level," said Jiang He, M.
After 4 weeks of thalassotherapy application benefits could be seen by means of a reduction in the arterial systolic blood pressure
WHR = Waist -Hip ratio,###WC = Waist circumference,###BF%= Body fat %###SBP= Systolic blood pressure
Results after 30 days of the trial were said to have demonstrated: an average blood pressure of 148 / 87 mmHg, a 28 point reduction in systolic pressure; and a reduction in systolic blood pressure
to below 140 mmHg in 41 % of patients.
The trial revealed a reduction in systolic blood pressure
associated with protein, but not carbohydrate, supplementation.
In a subgroup analysis of 30 volunteers who had the highest systolic blood pressure
readings (129 mm.
Researchers found that high systolic blood pressure
(the pressure when the heart contracts) is a powerful risk factor for cardiovascular complications in middle-aged and older women all over the world.