To put the potential impact of the findings into context, Juraschek says, the FDA requires any new antihypertensive agent submitted for approval to lower
systolic blood pressure by 3-4 mm Hg.
gov/pubmed/15752957) associated with
systolic blood pressure that is about 2.
Interpretation: Treating to a lower
systolic blood pressure goal of less than 120 mmHg may provide added benefit for patients who meet the study population criteria, but with potential risks.
One trial in the review (ACCORD, 4734 patients) compared outcomes from significantly lower and standard
systolic blood pressures (119/64 mm Hg vs 134/71 mm Hg; P<.
Esmolol 50 mg group adequately attenuated the heart rate but the
systolic blood pressure and diastolic blood pressure were not satisfactorily attenuated compared to esmolol 100 mg group.
The
systolic blood pressure differences we found are small for the individual, but they are important at the population level," said Jiang He, M.
After 4 weeks of thalassotherapy application benefits could be seen by means of a reduction in the arterial
systolic blood pressure.
WHR = Waist -Hip ratio,###WC = Waist circumference,###BF%= Body fat %###SBP=
Systolic blood pressureResults after 30 days of the trial were said to have demonstrated: an average blood pressure of 148 / 87 mmHg, a 28 point reduction in systolic pressure; and a reduction in
systolic blood pressure to below 140 mmHg in 41 % of patients.
The trial revealed a reduction in
systolic blood pressure associated with protein, but not carbohydrate, supplementation.
In a subgroup analysis of 30 volunteers who had the highest
systolic blood pressure readings (129 mm.
Researchers found that high
systolic blood pressure (the pressure when the heart contracts) is a powerful risk factor for cardiovascular complications in middle-aged and older women all over the world.
