systemic autoimmune diseases

sys·tem·ic au·to·im·mune dis·eas·es

a group of connective tissue diseases characterized by the presence of autoantibodies responsible for immunopathologically mediated tissue lesions; systemic lupus erythematosus is the prototype.

sys·tem·ic au·to·im·mune dis·eas·es

(sis-temik awtō-i-myūn di-zēzĕz)
Connective tissue diseases characterized by presence of autoantibodies responsible for immunopathologically mediated tissue lesions; systemic lupus erythematosus is the prototype.
References in periodicals archive ?
In the lab, Guthridge studies the causes and development of systemic autoimmune diseases like lupus, multiple sclerosis and Sjgren's syndrome.
Vasculitis can be classified as primary or secondary to identifiable causes like infectious agents, systemic autoimmune diseases or malignancy.
Antinuclear antibody (ANA) can be helper to the diagnosis of systemic autoimmune diseases (SAID) and to monitor disease activity.
Mortality and long term survival prognostic factors of patients with systemic autoimmune diseases admitted to an intensive care unit: a retrospective study.
In this case, it should be an initial manifestation of some systemic autoimmune diseases, such as SLE [17].
Immune diseases of the anterior segment of the eye may be caused by several local or systemic conditions and may present in a wide range of diseases including dry eye syndrome, ocular cicatricial pemphigoid (OCP), graft versus host disease (GVHD), and some forms of anterior uveitis often associated with systemic autoimmune diseases such as ankylosing spondylitis.
However, a large number of experimental and clinical cases of SSHL have been identified in which SSHL is a symptom associated with other autoimmune diseases or is the primary symptom of spontaneous systemic autoimmune diseases such as autoimmune hepatitis [2], sympathetic neural hyperalgesia edema syndrome [3], Cogan's syndrome [4, 5], systemic lupus erythematosus [6, 7], multiple sclerosis [8-10], rheumatoid arthritis [11], nodular polyarteritis [12], Crohn's disease [13], and so on.
Many systemic autoimmune diseases have otolaryngology manifestations that could represent a diagnostic challenge for clinicians, as they often constitute an early sign of an otherwise asymptomatic autoimmune condition and may lead to delayed diagnosis and treatment.
Cardiac involvement has been reported to be one of the main complications contributing to the morbidity and mortality of patients suffering from systemic autoimmune diseases. While pericardial involvement is the most common echocardiographic lesion in systemic lupus erythematosus (SLE) and the most frequent cause of symptomatic cardiac disease, myocarditis remains fairly uncommon [3].