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Related to systemic anaphylaxis: Anaphylactoid reactions
gen·er·al·ized an·a·phy·lax·is(jen'ĕr-ă-līzd an'ă-fi-lak'sis)
A reaction between IgE antibodies bound to mast cells and an allergen that causes the sudden release of immunological mediators in the skin, respiratory, cardiovascular, and gastrointestinal systems. The consequences may range from mild, e.g., itching, hives, to life-threatening (airway obstruction and shock).
See also: anaphylaxis