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Related to synthetase: Glutamine synthetase
ligase; any of a class of enzymes that catalyze the joining together of two molecules coupled with the breakdown of a pyrophosphate bond in ATP or a similar triphosphate.
Miller-Keane Encyclopedia and Dictionary of Medicine, Nursing, and Allied Health, Seventh Edition. © 2003 by Saunders, an imprint of Elsevier, Inc. All rights reserved.
An enzyme catalyzing the synthesis of a specific substance. Synthetase is limited, in the Enzyme Commission Report, to use as a trivial name for the ligases (EC class 6), which in turn are those synthesizing enzymes that require the cleavage of a pyrophosphate linkage in ATP or a similar compound. Reversal of lyase (EC class 4) reactions, producing a synthesis, is indicated (in trivial names) by synthase; such reactions do not involve pyrophosphate cleavage. For individual synthetases, see the specific names.
Farlex Partner Medical Dictionary © Farlex 2012
Any of a group of enzymes that catalyze the synthesis of a compound. Also called synthase.
The American Heritage® Medical Dictionary Copyright © 2007, 2004 by Houghton Mifflin Company. Published by Houghton Mifflin Company. All rights reserved.
An enzyme catalyzing the synthesis of a specific substance.
Medical Dictionary for the Health Professions and Nursing © Farlex 2012