synoviocytes

synoviocytes

cells of the synovial membrane are of two types: type A are mainly phagocytic and pinocytic; type B are chiefly synthesizers.
References in periodicals archive ?
Cells called fibroblast-like synoviocytes (FLS) play a major role in the disease.
Synovium is essential to joint homeostasis, since its vascular network is responsible for cartilage nutrition and because of the synoviocytes that produce synovial fluid (54).
More recently, the transient receptor potential canonical 5 (TRPC5) expressed on fibroblast like synoviocytes cells within the joint has been shown to protect against pain and inflammation in arthritic mice (54).
sup][19],[20],[21],[22],[23] Among these diseases, IL-21R can not only be expressed by a variety of lymphocytes but also by disease target cells such as fibroblast-like synoviocytes in patients with rheumatoid arthritis, neurons in patients with multiple sclerosis, and keratinocytes in patients with systemic sclerosis.
The effects of these inflammatory mediators in articular cartilage, chondrocytes and synoviocytes have been reported.
1] IL-17A binds to its receptors -IL-17 receptor A/IL-17 receptor C- on synoviocytes, endothelial cells, fibroblasts and osteoblasts and stimulates production of pro-inflammatory cytokines, chemokines and other inflammatory mediators, and also, interacts synergistically with other proinflammatory cytokines such as IL-1, IL-6, and tumor necrosis factor alpha.
Homocysteine enhances cytokine production in cultured synoviocytes from rheumatoid arthritis patients.
15) Fibroblast-like synoviocytes can circumvent healthy cell turnover and instead release inflammatory molecules via a protein complex called NF-kappaB.
AS is a water-soluble hemisuccinate derivative of dihydroartemisinin, and also possesses anti-cancer, anti-angiogenesis and anti-inflammatory activities in human rheumatoid arthritis fibroblast-like synoviocytes (Lai HC, et al, 2014; Wang Z, et al, 2012; Wang HY, et al, 2014.