Synovial tissue from the other RA patients showed vigorous proliferation of
synovial cells and infiltration of inflammatory cells, typical of the histopathological changes of RA.
Kingella kingae expresses type IV pili that mediate adherence to respiratory epithelial and
synovial cells.
When exposed to a culture of living
synovial cells, the concentrated extraction from avian origin was twice as efficacious at stimulating the production of more HA compared with the fermented product, even though the concentration of each product was the same (200 [micro]g/mL).
However, no correlations were obtained between the immunoreactivity and
synovial cell hyperplasia, fibrosis, or total scores (data not shown).
Researchers anywhere in the world will be able to order
synovial cells for arthritis research through Asterand's online catalogue at http://solutions.
Hematoxylin and eosin stained sections of samples obtained from the glenohumeral joint during arthroscopy showing synovial lined villous proliferation which is diffusely infiltrated by mature fat cells while the periphery is lined by hypertrophic
synovial cells and infiltrated by chronic inflammatory cells (bar size at lower right corner of images indicates 200 [micro]m panel (a) and 100 [micro]m panel (b)).
1) Mononuclear chronic inflammatory cells may be seen in the overlying synovial membrane and the
synovial cells may be reactive with eosinophilic cytoplasm.
The effects of methylprednisolone on
synovial cells in culture.
3) Through this stimulation, proliferation of the
synovial cells occurs and the production of inflammatory mediators and enzymes causes cartilage destruction, ultimately leading to the formation of a "pannus" (granulation tissue), which covers the articular surface.
Over this period of time, the resettlement and viability of
synovial cells were monitored photographically after 0, 24 and 48 h with an Olympus 1X71 microscope (Olympus, Hamburg, GER) and Olympus C-5060 digital camera.
While the cause of rheumatoid arthritis is unknown, microorganisms or some other cause are thought trigger the proliferation of
synovial cells, which line the inner surface of the joint cavity.
In addition, interaction of the chondrocytes with
synovial cells will enhance the negative effects on joint (Arthritis Rheum.
