syngeneic


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Related to syngeneic: syngeneic transplant

syngeneic

 [sin″jĕ-ne´ik]
in transplantation biology, denoting individuals or tissues having identical genotypes, i.e., identical twins or animals of the same inbred strain, or their tissues. Called also isogeneic and isologous.

syn·ge·ne·ic

(sin'jĕ-nē'ik),
Relating to genetically identical individuals.
[G. syngenēs, congenital]

syngeneic

/syn·ge·ne·ic/ (sin″jĕ-ne´ik) denoting individuals or tissues that have identical genotypes and thus could participate in a syngraft.

syngeneic

(sĭn′jə-nē′ĭk)
adj.
Genetically identical or closely related, so as to allow tissue transplant; immunologically compatible: syngeneic grafts; syngeneic mice.

syn·ge·ne′i·cal·ly adv.

syngeneic

[sin′jənē′ik]
Etymology: Gk, syn + genesis, origin
1 denoting an individual or cell that has the same genotype as another individual or cell.
2 denoting tissues that are antigenically similar. Also calledisogeneic.Compare allogenic, xenogeneic.

syn·ge·ne·ic

(sin'jĕ-nē'ik)
Relating to genetically identical individuals.
Synonym(s): isogeneic, isogenic, isologous, isoplastic.
[G. syngenēs, congenital]

Syngeneic

Referring to a bone marrow transplant from one identical twin to the other.

syngeneic

in transplantation biology, denoting individuals or tissues having almost identical genotypes, i.e. animals of the same inbred strain, or their tissues. Grafts can be as readily exchanged between syngeneic animals as between identical twins which are called isogeneic.
References in periodicals archive ?
In vitro study indicates the mechanisms of [beta]-catenin downregulation by EGCG, and in vivo study supports anti-tumorigenic activities of EGCG in a syngeneic mouse model.
Similar to the results reported previously that CD4+ T cells from the tolerant mice could transfer tolerance [5], we found that this long-lasting immune tolerance could also be transferred to syngeneic naive C3H mice through adoptive transfer of CD4+ T cells from the tolerant mice, demonstrating that CD4+ T cells from tolerant mice markedly suppressed alloantigen-induced anti-donor antibody development compared to CD4+ T cells transferred from immunized mice (Figures 2(a), 2(b), and 2(c)).
The donor was immunized with MAGE-A3 protein, and primed donor cells collected after immunization were transferred to her identical twin after syngeneic stem cell transplant, followed by repeated patient immunizations.
Citation: "Lack of Immune Response to Differentiated Cells Derived from Syngeneic Induced Pluripotent Stem Cells"; Prajna Guhaetal; Cell Stem Cell, 2013; DOI: 10.
Herb and Bert had found that the intense inflammatory response to local injection of BCG could produce regression of syngeneic hepatoma transplants growing on the flanks of guinea pigs, eliminate regional lymph node metastases, and induce tumor-specific immunity (9).
We have previously shown that inhibition of leptin signaling with pegylated leptin peptide receptor antagonist 2 (PEG-LPrA2) negatively impacted on the growth of mouse syngeneic and human breast cancer xenografts hosted by SCID mice, PEG-LPrA2 effects paralleled a significant reduction of VEGF/VEGFR2 levels.
Inhibitory effect of Cordyceps sinensis on spontaneous liver metastasis of Lewis lung carcinoma and B16 melanoma cells in syngeneic mice.
Intravenous infusion of syngeneic apoptotic cells by photopheresis induces antigen-specific regulatory T cells.
Cultured splenocytes were transferred into syngeneic mice, and 4 days after the transfer, the recipient mice were challenged with RW.
Patients receiving T-cell-depleted stem cells or syngeneic transplantation have a higher risk of relapse of their underlying disease.
Fetal wound repair results in scar formation in interleukin-10-deficient mice in a syngeneic murine model of scarless fetal wound repair.