syngeneic


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Related to syngeneic: syngeneic transplant

syngeneic

 [sin″jĕ-ne´ik]
in transplantation biology, denoting individuals or tissues having identical genotypes, i.e., identical twins or animals of the same inbred strain, or their tissues. Called also isogeneic and isologous.

syn·ge·ne·ic

(sin'jĕ-nē'ik),
Relating to genetically identical individuals.
[G. syngenēs, congenital]

syngeneic

/syn·ge·ne·ic/ (sin″jĕ-ne´ik) denoting individuals or tissues that have identical genotypes and thus could participate in a syngraft.

syngeneic

(sĭn′jə-nē′ĭk)
adj.
Genetically identical or closely related, so as to allow tissue transplant; immunologically compatible: syngeneic grafts; syngeneic mice.

syn·ge·ne′i·cal·ly adv.

syngeneic

[sin′jənē′ik]
Etymology: Gk, syn + genesis, origin
1 denoting an individual or cell that has the same genotype as another individual or cell.
2 denoting tissues that are antigenically similar. Also calledisogeneic.Compare allogenic, xenogeneic.

syn·ge·ne·ic

(sin'jĕ-nē'ik)
Relating to genetically identical individuals.
Synonym(s): isogeneic, isogenic, isologous, isoplastic.
[G. syngenēs, congenital]

Syngeneic

Referring to a bone marrow transplant from one identical twin to the other.

syngeneic

in transplantation biology, denoting individuals or tissues having almost identical genotypes, i.e. animals of the same inbred strain, or their tissues. Grafts can be as readily exchanged between syngeneic animals as between identical twins which are called isogeneic.
References in periodicals archive ?
Syngeneic bone marrow transplantation in patients with severe aplastic anemia (SAA) is rare, and usually requires pre-transplant conditioning to provide engraftment (3), (4).
Patients receiving T-cell-depleted stem cells or syngeneic transplantation have a higher risk of relapse of their underlying disease.
Fetal wound repair results in scar formation in interleukin-10-deficient mice in a syngeneic murine model of scarless fetal wound repair.
We tested secondary CTLs on day 4 for proliferation (Figure 5A) and on day 5 for lytic activity against syngeneic P815 targets (Figure 5B).
Shortly after discharge, the patient underwent syngeneic hematopoietic cell transplantation and two courses of high-dose chemotherapy with melphalan for Merkel cell carcinoma with the goal of temporary remission.
In a syngeneic bone marrow transplant patient (15), the infection presented as a 3-cm solitary pulmonary nodule, and after 6 weeks of antimicrobial treatment, the culture-positive nodule vanished.
Up to 50% regressions have been seen in syngeneic and human tumors, including human breast carcinomas.
There are three types of grafts: allogeneic--taking bone marrow from someone other than the patient; autologous--using bone marrow from the patient him/herself while in remission; and syngeneic taking bone marrow from a chromosomally identical twin.
Data demonstrate antitumor activity at well-tolerated doses of the inhibitor of fucosylation in several in vivo tumor models, including a syngeneic tumor vaccine model.
McFarland , PhD, University of Alabama at Birmingham Loss of SOCS3 in myeloid cells promotes a decreased M2 macrophage phenotype and an increased cytotoxic T-cell response in a syngeneic model of glioma Saturday, November 21, 3:30 - 5:00 pm
Adoptive cellular immunotherapy is when syngeneic activated T-cells are infused in patients to attack their cancers.
Mortality in syngeneic rat parabionts of different chronological age.