syngeneic


Also found in: Dictionary, Encyclopedia, Wikipedia.
Related to syngeneic: syngeneic transplant

syngeneic

 [sin″jĕ-ne´ik]
in transplantation biology, denoting individuals or tissues having identical genotypes, i.e., identical twins or animals of the same inbred strain, or their tissues. Called also isogeneic and isologous.

syn·ge·ne·ic

(sin'jĕ-nē'ik),
Relating to genetically identical individuals.
[G. syngenēs, congenital]

syngeneic

(sĭn′jə-nē′ĭk)
adj.
Genetically identical or closely related, so as to allow tissue transplant; immunologically compatible: syngeneic grafts; syngeneic mice.

syn·ge·ne′i·cal·ly adv.

syn·ge·ne·ic

(sin'jĕ-nē'ik)
Relating to genetically identical individuals.
Synonym(s): isogeneic, isogenic, isologous, isoplastic.
[G. syngenēs, congenital]

Syngeneic

Referring to a bone marrow transplant from one identical twin to the other.
References in periodicals archive ?
Johnson, "Depletion of CD4 T cells enhances immunotherapy for neuroblastoma after syngeneic HSCT but compromises development of antitumor immune memory," Blood, vol.
Our results indicate that nude mice with syngeneic human breast tumors that received rhBMP-2 either by IP injection or direct intratumoral injection exhibited microcalcifications detected by CT.
Approximately 37.5% (15 of 40) of the grafts in the allogeneic group underwent acute rejection 4 weeks after transplantation, while no graft in the syngeneic group was rejected (Figure 1(a)).
Transplantations were carried out by taking the bone marrow from related, matched donors (allogeneic transplantation) or from identical twins (syngeneic transplantation).
Wong, "Schizophyllan (SPG)-treated macrophages and anti-tumor activities against syngeneic and allogeneic tumor cells--I.
For example, mouse TBJ neuroblastoma [34] or C26 colon carcinoma cells [33], genetically engineered to express a single-chain IL-27 molecule, lost their tumorigenic potential when implanted in syngeneic mice.
Pollard, "Pharmacological ascorbic acid suppresses syngeneic tumor growth and metastates in hormone-refractory prostate cancer," In Vivo, vol.
Laureys et al., "Prevention of autoimmune destruction of syngeneic islet grafts in spontaneously diabetic nonobese diabetic mice by a combination of a vitamin [D.sub.3] analog and cyclosporine," Diabetes, vol.
Stem cells can be autologous, or from the patient's own body; allogeneic, or from a donor; and syngeneic, or from an identical twin.
Antitumor effects of EGCG in vivo were evaluated in a syngeneic mouse model and [beta]-catenin expression was checked in HNC patients' samples.
Mortality in syngeneic rat parabionts of different chronological age.