Isolation of synaptosomes
was performed as previously described .
The effect of spider toxin PhTx3-4, [omega]-conotoxins MVIIA and MVIIC on glutamate uptake and on capsaicin-induced glutamate release and [Ca2+]i in spinal cord synaptosomes
The aim of the present study is to further investigate the alstonine mechanism of action by analyzing its effects on D2R binding in relevant brain areas (through quantitative autoradiography) and dopamine uptake by striatal synaptosomes
Formation of phospholipid hydroperoxides and its inhibition by alpha-tocopherol in rat brain synaptosomes
induced by peroxynitrite.
iv) It inhibit the release of glutamate from synaptosomes
prepared from cerebral cortex.
In studies on forced swimming method in mice, it has been shown that beta-amyrin palmitate caused a release of [3H]norepinephrine in mouse brain synaptosomes
, suggesting that the compound might activate noradrenergic activity and this activity is responsible for the antidepressant effect .
Cerebral ischemia causes dysregulation of synaptic adhesion in mouse synaptosomes
Synaptic proteins and SNARE complexes are localized in lipid rafts from rat brain synaptosomes
In vitro neuroprotective effects including inhibition of presynaptic glutamate release [19, 20], attenuation of post-synaptic glutamate activity at NMDA and AMPA-receptors [19, 21], calcium accumulation inhibition in synaptosomes
, and nitric-oxide induced cytotoxicity inhibition .
ATPase activity induced by in vitro direct administration of morphine to isolated striatal synaptosomes
In rat striatal synaptosomes
METH-stimulated DAT T53 phosphorylation was rapid, occurring within 60 sec.
Effect of taurine on neurotransmitter release from insect synaptosomes