synaptosome


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syn·ap·to·some

(sin-ap'tō-sōm),
Membrane-bound sac containing synaptic vesicles that breaks away from axon terminals when brain tissue is homogenized under controlled conditions; such particles can be separated from other subcellular particles by differential and density gradient centrifugation.
[synapse + G. sōma, body]

synaptosome

(sĭ-năp′tə-sōm′)
n.
Any of various sacs, composed of synaptic vesicles and mitochondria, that break away from axon terminals at a synapse after brain tissue has been homogenized under controlled conditions.

syn·ap′to·so′mal adj.

syn·ap·to·some

(si-nap'tŏ-sōm)
Membrane-bound sac containing synaptic vesicles that breaks away from axon terminals when brain tissue is homogenized under controlled conditions; such particles can be separated from other subcellular particles by differential and density gradient centrifugation.
[synapse + G. sōma, body]
References in periodicals archive ?
The size distribution of S Vs at intact nerve endings (synaptosomes) and within SV-enriched fractions was compared using different preparation techniques to determine the mean diameter of SVs precisely (Fig.
We observed Pin1 protein and Shank3 protein in synaptosome from cortical tissues of human control brains showed associated together by immunoprecipitation (Figure 4(a)).
In freshly isolated synaptosomes, they differentiate mitochondrial-dependent consumption of molecular oxygen from that consumed through NADPH oxidase (NOX) while concomitantly defining [H.sub.2][O.sub.2] generation.
The detached nerve terminals from skate electric organ deserve comparison with "synaptosomes," which are formed by homogenizing Torpedo electric organ.
This included the increased accumulation of dopamine in synaptosomes due to delayed efflux.
Its specific association with synaptic vesicles demonstrated by immuno cytochemistry in agarose- embedded synaptosomes. J Cell Biol 1983;96:1355-73.
Chronic treatment with agomelatine or venlafaxine reduces depolarization-evoked glutamate release from hippocampal synaptosomes. BMCNeurosci 2013; 14: 75.
(6) Study on mice synaptosomes has shown reduction of brain-derived neurotrophic factor (BDNF) within 1-6 days post LPS injections and maximum reduction at day 3.
It is isolated in small amounts from brain synaptosomes in the form of glutaurine, which acts as a neurotransmitter.
Colhoun, "Evidence for high affinity choline transport in synaptosomes prepared from hippocampus and neocortex of patients with Alzheimer's disease," Brain Research, vol.
Schwalm et al., "Methylmercury increases glutamate release from brain synaptosomes and glutamate uptake by cortical slices from suckling rat pups: Modulatory effect of ebselen," Toxicological Sciences, vol.