synaptic transmission


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synaptic transmission

The release of a neurotransmitter by a neuron that initiates or inhibits an electrical impulse in the next neuron in the pathway.
See also: transmission
References in periodicals archive ?
(1) In short, Gene Ontology analysis has identified several potentially affected pathways involved in synaptic transmission (HTR2A, BDNF, CHRNA3, CHRNB4, DRD1, DRD2, DRD4, EGR1, GRIA4, GRIN2B, GRM3, NISCH, SLC1A3, and ERBB4), dopamine metabolic processes (COMT, DRD1, DRD2, DRD4, MAOA, NR4A2, and SLC6A3), and ion channel activity (CHRNA7, CACNA1I, CACNB2, CHRNA3, CHRNA5, CHRNB4, GABRB3, GRIA4, GRIA1, GRIN2B, HCN1, CACNA1C, KCTD13, KCNV1, KCNN3, KCNJ13, and KCNB1).
Rouach, "How do astrocytes shape synaptic transmission? Insights from electrophysiology," Frontiers in Cellular Neuroscience, vol.
Relative to glutamate dysfunction believed to underlie negative symptoms and cognitive deficits of schizophrenia, ectopic mossy fiber guidance is likely another contributing factor, resulting in dysregulated excitatory synaptic transmission within the hippocampal circuits, particularly in the CA3 subfield.
The reduced activation of GluA/N receptors may seem detrimental, as it weakens the strength of excitatory synaptic transmission. The high-pass filtering effect may also be disruptive as it promotes high-frequency activity and seizure propagation in the brain.
Neugebauer, "Facilitation of synaptic transmission and pain responses by CGRP in the amygdala of normal rats, "Molecular Pain, vol.
Aside from the changes in cell excitability, the inhibition of neural network activity induced by A[beta] has also been related to a reduction in both excitatory [34, 37, 47, 48] and inhibitory [47, 48] synaptic transmission. In fact, these findings are consistent with the observation that A[beta] reduced cholinergic modulation of the inhibitory transmission in the PFC [17].
Neonatal propofol exposure impairs glutamatergic tonic regulation of spontaneous inhibitory synaptic transmission
(18,19) Synaptic transmission is triggered by the influx of [Ca.sup.2+] to the presynaptic membrane and then neurotransmitters such as glutamate, acetylcholine, and GABA are released in the form of vesicles.
Conclusion: These results indicate that TEN enhances the basic synaptic transmission via stimulating presynaptic intracellular calcium.
(2000) "Effects of hemoglobin and its breakdown products on synaptic transmission in rat hippocampal CA1 neurons", Brain Res.
As mentioned previously, Wang and colleagues (2010) have described an increase in NMDAR-mediated synaptic transmission that begins just after the end of an acute exposure to ethanol and which seems to be largest in the DMS (figure 1C).
This model derives from the observation that the cyst is structurally a vesicle inasmuch as it is enveloped by a membrane (Watson and Mariscal, 1984; Golz, 1994), and the assumption that one of the first steps in discharge would likely be fusion of the cyst membrane with the cell membrane, as occurs during synaptic transmission and other exocytotic processes (Lubbock et al., 1981).