secondary generalized epilepsy

(redirected from symptomatic epilepsy)

sec·on·dar·y gen·er·al·ized ep·i·lep·sy

a group of epilepsy syndromes of diverse etiologies with diffuse or multifocal cerebral involvement. Patients typically have a variety of generalized seizure types, including tonic, atonic, myoclonic, atypical absence, and generalized tonic-clonic seizures. Partial seizures may also occur. One classic syndrome is the Lennox-Gastaut syndrome.
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(5) described the occurrence of seizures in the first 14 days of CVT as acute symptomatic epilepsy (ASE) in their meta-analysis and observed ASE in patients with altered consciousness and focal neurologic deficits and with supratentorial lesions.
Twenty-two (21.4%) patients had unknown etiology and 81 (78.6%) had symptomatic epilepsy. The most common identifiable etiology of symptomatic seizures was autoimmune epilepsy in 43 (41.7%) patients including 38 (36.9%) with autoimmune encephalitis and five (4.9%) with paraneoplastic neurological syndrome.
More than half of the patients (55%, n=11) had an unknown etiology for SE, while other causes were anoxic brain injury (10%, n=2), non anoxic brain injury and systemic causes (20%, n=4), remote symptomatic epilepsy (15%, n=3).
We hypothesised that psychiatric and behavioural problems would be more prevalent among children /adolescents with epilepsy than those without, and that children / adolescents with symptomatic epilepsy would have more problems than those with idiopathic epilepsy.
Muzny et al., "Whole exome sequencing identifies the first STRADA point mutation in a patient with polyhydramnios, megalencephaly, and symptomatic epilepsy syndrome (PMSE)," American Journal of Medical Genetics A, vol.
Symptomatic epilepsy is defined as epilepsy of predominantly in which the epileptic seizures are the result of one or more acquired or genetic cause that are related to the malfunctions in the gross anatomic or pathologic anomalies: for instance, the epilepsy owing to tuberous sclerosis, neurofibromatosis, posttraumatic, and infections.
Out of 112 patients with epilepsy, symptomatic epilepsy was by far the most common type of epilepsy in this study (78.6%) followed by idiopathic epilepsy 12 (10.7%) and cryptogenic epilepsy 10 (8.9%).
A 28-year-old woman was diagnosed with symptomatic epilepsy (generalised tonic-clonic) at the age of 5 after leaving our hospital with Japanese encephalitis.
There are also cases of symptomatic epilepsy which may be due to road accidents, infection or stroke and cardiovascular issues in elderly people.
It generally occurs as a manifestation of an acute precipitating event affecting the CNS or an exacerbation of symptomatic epilepsy. Slightly less than 10% of the cases are idiopathic.
This correlates with a higher incidence of symptomatic epilepsy. Recurrence rates are lowest in children with no clear aetiology or suspected genetic aetiology (approximately 30%).

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