sympathomimetic


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sympathomimetic

 [sim″pah-tho-mi-met´ik]
1. producing effects resembling those of impulses transmitted by the postganglionic fibers of the sympathetic nervous system. See also adrenergic.
2. an agent that produces such an effect.

sym·pa·tho·mi·met·ic

(sim'pă-thō-mi-met'ik),
Denoting mimicking of action of the sympathetic system.
See also: adrenomimetic.
[sympatho- + G. mimikos, imitating]

sympathomimetic

/sym·pa·tho·mi·met·ic/ (-mi-met´ik)
1. mimicking the effects of impulses conveyed by adrenergic postganglionic fibers of the sympathetic nervous system.
2. an agent that produces such an effect.

sympathomimetic

(sĭm′pə-thō-mĭ-mĕt′ĭk, -mī-)
adj.
Producing physiological effects resembling those caused by the activity or stimulation of the sympathetic nervous system: a sympathomimetic hormone.
n.
A sympathomimetic drug or agent.

sympathomimetic

[sim′pəthō′mimet′ik]
Etymology: Gk, sympathein + mimesis, imitation
a pharmacological agent that mimics the effects of stimulation of organs and structures by the sympathetic nervous system. It functions by occupying adrenergic receptor sites and acting as an agonist or by increasing the release of the neurotransmitter norepinephrine at postganglionic nerve endings. Various sympathomimetic agents are used as decongestants of nasal and ocular mucosa, such as bronchodilators in the treatment of asthma and vasopressors and cardiac stimulants in the treatment of acute hypotension and shock; they are also used for maintaining normal blood pressure during operations using spinal anesthesia. Drugs in this group include cyclopentamine, DOBUTamine, DOPamine, epHEDrine, isoproterenol, metaproterenol, metaraminol, mephentermine, methoxamine, methoxyphenamine, naphazoline, norepinephrine, phenylephrine, propylhexedrine, protokylol, pseudoephedrine, terbutaline sulfate, tetrahydrozoline, tuaminoheptane, xylometazoline, and epINEPHrine, a synthetic isomer of the hormone secreted by the adrenal medulla. Adverse effects of sympathomimetic drugs may be nervousness, severe headache, anxiety, vertigo, nausea, vomiting, dilated pupils, glycosuria, and dysuria. Also called adrenergic drug.

sym·pa·tho·mi·met·ic

(sim'pă-thō-mi-met'ik)
Denoting mimicking of action of the sympathetic system.
See also: adrenomimetic
Synonym(s): sympathicomimetic.
[sympatho- + G. mimikos, imitating]

sympathomimetic

Of any agent that simulates or stimulates the sympathetic nervous system. ADRENERGIC. Sympathomimetic action can increase the heart output by 100 per cent over resting values. It can constrict arteries and increase the blood pressure. And it can widen the air tubes of the lungs allowing more free access of large volumes of air.

Sympathomimetic

Denoting a drug that mimics the effects of stimulation of organs and structures by the sympathetic nervous system. The sympathetic nervous system pertains to the part of the nervous system originating in the thoracic and lumbar regions of the spinal cord. In general, it inhibits or opposes the physiological effects of another aspect of the nervous system, as in tending to reduce digestive secretions, speed up the heart, and contract the blood vessels.
Mentioned in: Tilt Table Test

sym·pa·tho·mi·met·ic

(sim'pă-thō-mi-met'ik)
Denoting mimicking of action of sympathetic system.
[sympatho- + G. mimikos, imitating]

sympathomimetic

adrenergic: producing effects resembling those of impulses transmitted by the postganglionic fibers of the sympathetic nervous system. Also, an agent that produces such an effect.
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Prevent response to laryngoscopy with magnesium or opioid Amphetamines Seizures, proteinuria, May be mistaken for hypertension pre-eclampsia (as cocaine) Fetal distress and May require emergency placental abruption caesarean section Psychedelic effects May cause problems placing regional block Hypertension, myocardial Caution with ischaemia, arrhythmias sympathomimetic agents.
In this respect, the green tea extract is distinct from sympathomimetic drugs, whose use as antiobesity thermogenic agents is limited by their adverse cardiovascular effects and, hence, is particularly inappropriate for obese individuals with hypertension and other cardiovascular complications.
This synthetic cathinone, derived from an African shrub, is a stimulant and sympathomimetic agent.
Unlike sympathomimetic drugs and ephedrine, however, green tea extracts do not increase heart rate and are not associated with adverse cardiovascular effects.
Toxicities result from the drug's sympathomimetic properties, which lead to hypertension and vasoconstriction, causing decreased uterine blood flow and fetal hypoxia.
Possible overdose with a sympathomimetic agent such as cocaine.
4] These medications can produce dangerously high levels of norepinephrine because the MAOI impairs the metabolism of sympathomimetic medications.
Sibutramine, a norepinephrine reuptake inhibitor that has sympathomimetic effects, was withdrawn from the European market in January, based on the SCOUT results.
At a meeting last month, the FDB)s Endocrinologic and Metabolic Drugs Advisory Committee reviewed data from two clinical trials of the combination product that contains an immediate-release formulation of phentermine, which is a sympathomimetic amine approved as an obesity treatment, and a controlled-release formulation of topiramate, an antiepileptic drug approved for treating seizures and migraines.
3,4) The analysis was not able to identify any differential effect of these beta-blockers with or without intrinsic sympathomimetic activity for patients with lung disease.