sympatholytic


Also found in: Dictionary, Encyclopedia, Wikipedia.

sympatholytic

 [sim″pah-tho-lit´ik]
1. blocking transmission of impulses from the adrenergic (sympathetic) postganglionic fibers to effector organs or tissues, inhibiting such sympathetic functions as smooth muscle contraction and glandular secretion.
2. an agent that produces such an effect; called also antiadrenergic.

sym·pa·tho·lyt·ic

(sim'pă-thō-lit'ik),
Denoting antagonism to or inhibition of adrenergic nerve activity.
See also: adrenergic blocking agent, antiadrenergic.
[sympatho- + G. lysis, a loosening]

sympatholytic

/sym·pa·tho·lyt·ic/ (-lit´ik)
1. antiadrenergic; opposing the effects of impulses conveyed by adrenergic postganglionic fibers of the sympathetic nervous system.
2. an agent that so acts.

sympatholytic

(sĭm′pə-thō-lĭt′ĭk)
adj.
Opposing the physiological effects caused by stimulation of the sympathetic nervous system: a sympatholytic treatment.

sympatholytic, sympatholytic agent

sym·pa·tho·lyt·ic

(sim'pă-thō-lit'ik)
Denoting antagonism to or inhibition of adrenergic nerve activity.
See also: adrenergic blocking agent, antiadrenergic
Synonym(s): sympathicolytic.
[sympatho- + G. lysis, a loosening]

sympatholytic

antagonism (inhibition) of sympathetic activity (i.e. of adrenergic nerves)

sym·pa·tho·lyt·ic

(sim'pă-thō-lit'ik)
Denoting antagonism to or inhibition of adrenergic nerve activity.
[sympatho- + G. lysis, a loosening]

sympatholytic (sim´pəthōlit´ik),

adj pertaining to a drug that blocks the effects of stimulation of the sympathetic nervous system. See also adrenolytic.

sympatholytic

antiadrenergic: blocking transmission of impulses from the adrenergic (sympathetic) postganglionic fibers to effector organs or tissues, inhibiting such sympathetic functions as smooth muscle contraction and glandular secretion. Also, an agent that produces such an effect.
References in periodicals archive ?
Because dexmedetomidine possesses anxiolytic, sedative, analgesic, and sympatholytic properties (13, 22, 28-31), it might be a useful adjunct for premedication, especially for patients susceptible to preoperative and perioperative stress.
2]-adrenoceptor agonists may prove beneficial in the postoperative period because of their sympatholytic and analgesic effects without respiratory depression.
Hypotension with a relative bradycardia could be due to sympatholytics (think of beta-blockers, opiates), membrane depressants (think of quinidine, tricyclics) and others (think of fluoride, organophosphates, sedative-hypnotics).
Researchers believe this sympatholytic effect likely contributed to an associated 41% reduction in the risk of developing AF for the 1,202 Gencaro patient cohort without AF at baseline.
Ryan Aleong, Assistant Professor of Medicine, Cardiology, Director of Implanted Cardiac Device Clinic, University of Colorado Hospital, and Interim Director of Arrhythmia Services at Denver Health Medical Center, presented "Bucindolol's Sympatholytic Properties Contribute to Reduction in the Risk of Developing New Onset Atrial Fibrillation in Patients with Advanced Heart Failure" during the session "Arrhythmias: AF/SVT: Continuing Role of Pharmacologic Therapy for Atrial Arrhythmias," Monday, March 26, 2012, 11:00am - 12:00pm Central.
Ryan Aleong, Assistant Professor of Medicine, Cardiology, Director of Implanted Cardiac Device Clinic, University of Colorado Hospital, and Interim Director of Arrhythmia Services at Denver Health Medical Center, is scheduled to present "Bucindolol's Sympatholytic Properties Contribute to Reduction in the Risk of Developing New Onset Atrial Fibrillation in Patients with Advanced Heart Failure" during the session "Arrhythmias: AF/SVT: Continuing Role of Pharmacologic Therapy for Atrial Arrhythmias," Monday, March 26, 2012, 11:00am - 12:00pm Central.
Bucindolol is a novel beta-adrenergic receptor blocking agent that lowers systemic norepinephrine in heart failure patients and thus is also a sympatholytic agent.