sympatholytic


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sympatholytic

 [sim″pah-tho-lit´ik]
1. blocking transmission of impulses from the adrenergic (sympathetic) postganglionic fibers to effector organs or tissues, inhibiting such sympathetic functions as smooth muscle contraction and glandular secretion.
2. an agent that produces such an effect; called also antiadrenergic.

sym·pa·tho·lyt·ic

(sim'pă-thō-lit'ik),
Denoting antagonism to or inhibition of adrenergic nerve activity.
See also: adrenergic blocking agent, antiadrenergic.
[sympatho- + G. lysis, a loosening]

sympatholytic

(sĭm′pə-thō-lĭt′ĭk)
adj.
Opposing the physiological effects caused by stimulation of the sympathetic nervous system: a sympatholytic treatment.

sym·pa·tho·lyt·ic

(sim'pă-thō-lit'ik)
Denoting antagonism to or inhibition of adrenergic nerve activity.
See also: adrenergic blocking agent, antiadrenergic
Synonym(s): sympathicolytic.
[sympatho- + G. lysis, a loosening]

sym·pa·tho·lyt·ic

(sim'pă-thō-lit'ik)
Denoting antagonism to or inhibition of adrenergic nerve activity.
[sympatho- + G. lysis, a loosening]
References in periodicals archive ?
Bromocriptine: A Sympatholytic, D2-Dopamine Agonist for the Treatment of Type 2 Diabetes.
Since melatonin exerts cardiovascular protection on several levels including antioxidant and scavenging actions [21-23], endothelial protection, sympatholytic effect [24-28], and antiarrhythmic effects [29], it is comprehensible that a deficiency of melatonin could result in pathological alterations in circulation and target organ damage [2, 8].
"The size and durability of the antihypertensive, renal and sympatholytic effects of renal denervation, the long-term safety, improvement of quality of life, the possibility to relax antihypertensive drug treatment, the cost-effectiveness, and long-term, hard cardiovascular-renal outcomes still remain to be firmly established," wrote Dr.
Whether the regional sympatholytic effect of epidural block is of benefit is unclear.
The 6th chapter in a similar way of the 5th, deals with sympatholytic and sypathomimetic medicines.
Pronounced hypotensive effect was detected: decreased average daily, daytime and nighttime SBP and DBP, the indicators \"pressure load\" - SBP and DBP IV for a day, day and night, morning rise in the value decreased SBP variability in SBP and DBP for the day, night and day; circadian rhythm of blood pressure normalized in 15% of patients, which was the result of sympatholytic and vazodillatatic effects of a decrease in the activity of the RAAS: a marked decrease in the level of renin in the giperreninovom profile (p <0.05) decrease in aldosterone (P <0.05).
(19) suggested that fibromyalgia patients have norepinephrine-evoked pain which may be resolved by sympatholytic maneuvers.
As it is well known, the effect of nitroglycerine test includes both sympatholytic and peripheral antispasmodic component.
Because of its sympatholytic and vagomimetic actions, dexmedetomidine is approved with a warning about hypotension, bradycardia and sinus arrest and can be used only in a monitored situation.
Bromocriptine is a sympatholytic dopamine D2 receptor agonist that can "exert inhibitor effects on serotonin in the central nervous system," according to a ClinicalTrials.gov summary of a phase III study of Cycloset.