In addition to biological variability and some CF transmembrane conductance regulator mutations, false negative
sweat testing may occur due to technical errors (13).
Data from 2005 from the Red Cross War Memorial Children's Hospital CF clinic cohort in Cape Town indicated that the median age of diagnosis and survival age during the preceding 33 years were 6 months and 19.8 years, respectively.[3] Absence of newborn screening, limited access to
sweat testing for diagnosis and restricted availability of expensive CF medications (such as inhaled rhDNAse) or lung transplantation are barriers to improving CF survival in SA.
- US-based
sweat testing specialist ELITechGroup Biomedical Systems has release the new FDA-cleared Macroduct Advanced Sweat Collection System, the company said.
Newborns identified with meconium ileus should also have
sweat testing performed before a diagnosis of CF may be made (13).
Massie, "The relevance of
sweat testing for the diagnosis of cystic fibrosis in the genomic era," Clinical Biochemist Reviews, vol.
"
Sweat testing in opioid users with a sweat patch," Journal of Analytical Toxicology, 20(6): 393-397.
He helped develop the National Guidelines for acute asthma in children,
sweat testing and neonatal screening.
The CF Foundation (CFF) published specific guidelines for
sweat testing performed by laboratories across the United States.
"We also did
sweat testing and had some people from Loughborough here to help.
[3.] Clarke A., Burn J.:
Sweat testing to identify female carriers of X-linked hypohidrotic ectodermal dysplasia.
Physicians in our environment have become increasingly aware of this atypical form of CF and have a lower threshold for diagnostic testing, including
sweat testing and genotyping.
Inconsistencies in
sweat testing in UK laboratories.