(9) was to compare the sweat test
method and the neutron activation method.
Abnormal CFTR function in sweat glands manifests as impaired salt (NaCl) reabsorption and is the physiological basis of the sweat test
. The recognition of milder or atypical forms of CF associated with mild CFTR mutations and residual CFTR function has led to revision by the International Cystic Fibrosis Foundation of the lower limit of the sweat chloride reference range in the intermediate zone to 30 mmol/L for all ages (previously 40 mmol/L) (Table 1).
It was impossible to distinguish between the renal and systemic types because the sweat test
was not available.
Briefly, the sweat test
requires the use of iontophoresis to deliver pilocarpine, which causes sweat glands to secrete sweat.
Almost all patients who carried R334W in both homozygote and heterozygous forms had respiratory problems, pancreatic insufficiency and high sweat test
with diagnosis age of below 1 year.
The child diagnosed with cystic fibrosis would normaly be tested by the sweat test
as elevated sweat chloride is diagnostic for cystic fibrosis.
Patients under the age of 21 years with cystic fibrosis confirmed by sweat test
or genetic study receiving care at the outpatient clinics of a Teaching Hospital were included.
This article will introduce the basics of cystic fibrosis (CF), a variety of mutations within the defect, discuss testing for the disease through Sweat Test
versus genetic testing, and modes of treatments and therapies.
So Frey, working with Bishop, Wool&Prince then-creative director Katie Elks '12, and students, devised a "simulated sweat test
" to grow bacteria on 10 different swatches of fabric, and validated Bishop's claim.
The sweat test
was found to be 37 mmol/L and the repeated sweat test
was found to be 32 mmol/L.
The sweat test
for CF involves 3 consecutive procedures.
could not be performed successfully due to lack of production of sweat, therefore cystic fibrosis (CF) was excluded on the basis of history, absence of faecal fat and negative Delta-508 mutation (only available test for CF mutation).