We have just laid down some critical fundamentals of sweat gland and sweat duct
biology," Lu says.
In fact, the attribution of sweat gland neoplasms to eccrine or apocrine categories is often controversial,[15,17] because most sweat gland carcinomas seem to recapitulate sweat ducts
, which are histologically similar in eccrine and apocrine glands.
However, the affiliation appears not to be direct, because of the lack of evidence of direct dyskeratosis or occlusion of sweat ducts
by the leukemic infiltrates.
People prone to Prickly Heat often find that taking regular saunas before going on tropical holidays helps by acclimatising the sweat ducts
The sweat travels to the skin surface through sweat ducts
- special passageways for the cooling liquid.
Tiny blood vessels in the dermis, the deeper layer of skin, become thick-walled yet leakier, and there is a general loss of hair, nerve cells, sweat ducts
and sebaceous glands that produce fatty secretions called sebum.
Anti- perspirants work by plugging the sweat ducts
, which reduces the amount of sweat that reaches the skin.
17) Since eccrine sweat gland secretion is cholinergically mediated, the ability to inactivate secretion via direct cholinergic receptor blockade appears more attractive tha n merely occluding sweat ducts
with aluminum chloride or iontophoresis.
To reduce sweating, you need to use an anti-perspirant, which contains zirconium or aluminium salts which plug the sweat ducts
to stop excessive wetness.