A brief targeted review of susceptibility factors
, environmental exposures, asthma incidence, and recommendations for future asthma incidence research.
For population-level contextual analyses of susceptibility factors
, disparities, and asthma, see Gold and Wright (2005), and for a thorough review of cohort studies on asthma incidence, see King et al.
Additional research is also needed to understand the contribution of environmental exposure, endogenous susceptibility factors
, and increasing age in the disease linkage.
Host susceptibility factors
being investigated include age, gender, underlying disease, infections, and genetic factors.
The changes in liver pathology with griseofulvin are similar to those found with human erythropoietic protoporphyria (EP)-associated liver failure that occurs in a subset of patients and probably depends on genetic and physiologic susceptibility factors
to determine its onset (Bloomer et al.
The authors are evaluating whether genetic and other susceptibility factors
influence risk from these exposures.
Nutritional deficits Vitamins A, C, E Socioeconomic stressors