surface-enhanced laser desorption-ionization

surface-enhanced laser desorption-ionization

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SELDI

A technique to separate and image molecules, e.g., DNA or proteins, in biological samples. Molecules are captured on a protein chip, ionized, and imaged. This technique can be used to map the molecules in samples of blood or other bodily fluids.
References in periodicals archive ?
Surface-enhanced laser desorption-ionization retentate chromatography mass spectrometry (SELDI-RC-MS): a new method for rapid development of process chromatography conditions.
Surface-enhanced laser desorption-ionization (SELDI), originally described by Hutchens and Yip (38), overcomes many of the problems associated with sample preparations inherent with MALDI-MS.
[5] Nonstandard abbreviations: 2-DE, two-dimensional electrophoresis; MS, mass spectrometry; RCC, renal cell carcinoma; MALDI, matrix-assisted laser- desorption ionization; TOE, time of flight; SELD1, surface-enhanced laser desorption-ionization; BPH, benign prostatic hyperplasia; PSA, prostate-specific antigen; DWT, Discrete Wavelet Transform; and PCA, principal components analysis.
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