An fMRI study of the role of
suprapontine brain structures in the voluntary voiding control induced by pelvic floor contraction.
While the basic respiratory rhythm in normal situations is maintained by the impulses discharged by the dorsal group of neurons, the pneumotaxic center indirectly controls the duration of inspiration and helps in relying the
suprapontine impulses which promote voluntary inspiration and expiration (3).
Neurogenic OAB seems to arise from either increased afferent input from the bladder, abnormal central processing of afferent input leading to reduced
suprapontine inhibition or physical damage to the axonal paths integral to micturition reflex organized in spinal cord.
This constellation of symptoms and signs indicates a
suprapontine dysfunction.
There may also be changes related to
suprapontine disruptions.
