supraphysiologic

su·pra·phys·i·o·log·ic

, supraphysiological (sū'pră-fiz'ē-ō-loj'ik, -loj'i-kăl),
Denoting any dose (of a chemical agent that either is or mimics a hormone, neurotransmitter, or other naturally occurring agent) that is larger or more potent than would occur naturally, or the effects of such a dose. Compare: homeopathic (2), pharmacologic (2), physiologic (4).

supraphysiologic

adjective Endocrinology Referring to administration of hormones or other substances that are normally present in the circulation, in doses in excess of those normally produced by the body. Cf Homeopathic, Pharmacologic, Physiologic.

supraphysiologic

, supraphysiological (soo″pră-fiz″ē-ŏ-loj′ik) (-loj′ĭ-kăl)
Exceeding what is normally found in healthy individuals. The term is usually used to refer to a hormone or medication given in a stronger dose than the amount the body can produce on its own.
References in periodicals archive ?
The investigators first tested the effects of physiologic and supraphysiologic doses of sucralose on human adipose-derived mesenchymal stromal cells (MSCs).
Sen and his colleagues first tested the effects of both physiologic and supraphysiologic doses of sucralose on human adipose-derived mesenchymal stromal cells (MSCs).
Although the amount of IGF1 injected to mice here (total 400 [micro]g per mice) seemed to be at supraphysiologic levels, the same or higher IGF1 administration never caused destructive effects on homeostasis of rodents in the previous reports (32, 33); then it was concluded that the present of IGF1, solely on the uterus, could be evaluated properly.
The mechanism responsible for the supraphysiologic gonadotropin surge in females treated with gonadotropin-releasing hormone (GnRH) agonist and primed with GnRH antagonist.
The influence of supraphysiologic estradiol levels on human nidation.
5,6] Supraphysiologic BP ought to be avoided, as it may add to ventricular strain and increase endothelial dysfunction by increasing shear stress in the constricted pulmonary circuit.
This accumulated oxalate in termite gut is toxic and affects renal tubular cells at supraphysiologic concentrations, hence oxalate is a part of chemotherapy as anti-termite dose (7).
The effects of supraphysiologic doses of testosterone on muscle size and strength in normal men.
Verkoelen, "Oxalate is toxic to renal tubular cells only at supraphysiologic concentrations," Kidney International, vol.
They demonstrated that, when stressed with supraphysiologic forces, the femur retains its axial stability even after harvesting large corticocancellous flaps (up to 24 cm) from its medial aspect [35].
Postoperative retrograde urethrogram injected using 200 cc of dilute contrast at supraphysiologic pressures demonstrates persistence of a small cavity behind the posterior urethra, but no direct tract between the urethra and this cavity.
A 1995 report showed that superoxide generated by autoxidation of pyrogallol was quenched by nicotinic acid only at supraphysiologic concentrations.